endocrine system Flashcards
The multiple activities of the cells, tissues, and organs of the body are coordinated by the inter-play of several types of chemical messenger systems.
COORDINATION OF BODY FUNCTIONS BY CHEMICAL MESSENGERS
These are released by axon terminals of
neurons into the synaptic junctions and act locally to control nerve cell functions
NEUROTRANSMITTERS
These are released by the glands or the
specialized cells into the circulating blood and influence the function of target cells into another location in the body.
ENDOCRINE HORMONES
These are secreted by neurons into the circulating blood and influence the function of target cells to another
location of the body.
NEUROENDOCRINE HORMONES
Are secreted by the cells to the extra-
cellular fluid and affect neighboring target cells at a different type
PARACRINES
Are secreted by cells into the extra-
cellular fluid and affect the function of the same cells that produce them
AUTOCRINES
These are peptides secreted by cells to
the extra-cellular fluid and can function as autocrine, paracrine, or endocrine hormones
cytokines
are secreted by helper cells and act on other cells in the immune system and they are under the cytokines
cytokines
are chemical substances that are secreted by endocrine cells into the extra-cellular fluids and regulate the metabolic activity of other cells in the body.
Hormones
It affects target organs found throughout the body
Hormones
these are hormones that are secreted by anterior and posterior pituitary gland. Th pancreas and parathyroid gland.
PROTEINS AND POLYPEPTIDES
the hormones secreted by adrenal cortex and the ovaries, testes, and placenta
STEROID
what organ produces proteins and polypeptides?
pancreas and parathyroid glands
what organ produces steroids?
Adrenal cortex, ovaries, testes and placenta
Secreted by the thyroid and adrenal medulla
Derivatives of tyrosine
what do you call polypeptides with 100 or more amino acids?
proteins
fewer amino acids are referred to as?
Peptides
are hormones that synthesizes on the rough end of the endoplasmic reticulum in the same fashion as other proteins
Protein and peptide hormones
an organelle that is stored within the cytoplasm and many our bound into the cell membrane until their secretion is needed
Vesicles
what hormones are increased when calcium ions are also increased?
cyclicAMP (Cyclic adenosine monophosphate)
a hormone that is usually synthesized from cholesterol and are not stored
steroid hormones
what chemical structure of steroid hormones are similar to?
Cholesterol
what hormones are lipid soluble that consist of three cyclohexyl rings and cyto pentyl rings?
Steroid hormones
describe the appearance of steroid hormones
chemical structure is same like the cholesterol and it has three cyclohexyl rings and cyto pentyl rings that are combined into a single structure
where are much of the cholesterol producing cells come from?
Plasma
are hormones derived from tyrosine
Amine
what are the two glands that produces the 2 groups of hormones derived from tyrosine?
Thyroid gland and adrenal medullary hormone
the two groups of hormones from the thyroid gland and adrenal medullary hormones are formed by the __________ and _________ of the _______ cells
enzymes and cytoplasmic compartments, glandular cells
is one of the characteristics of endocrine glands.
Feedback
prevents overactivity of hormone systems. After a stimulus causes a release of hormone conditions of products resulting from the action of hormone tends to suppress its further release.
negative feedback
it occurs when a biological action of the hormone causes additional secretion of the hormone
positive feedback
a variation that occurs in hormone release
Cyclical variations
a variation of hormone that are influenced by seasonal changes, various stages of development and aging or the daily cycle and sleep.
Periodic variations
What variation is the secretion of growth hormones?
Periodic variations
secretion of growth hormones occurs during?
sleeping time
are hormones that are dissolved in the plasma and transported from their sites of synthesis to target cells/tissues?
Water-soluble hormones
Circulate in the blood while being mainly bound to plasma proteins
Steroid and thyroid hormones
how many percent of steroid or thyroid hormones exist freely in the plasma?
less than 10% of the solution
cannot easily diffuse across the capillaries and gain access to their target cells and are therefore biologically inactive until they dissociate from plasma proteins
protein-bound hormones
what are the ways that hormones are cleared from the plasma?
➢ Metabolic destruction by the tissues
➢ Binding with the tissues
➢ Excretion by the liver into the bile
➢ Excretion by the kidneys into the urine
what membrane are specific mostly for the protein, peptide, and catecholamine
hormone
membrane receptors
membrane receptors are specific mostly for the ________ , ________ and ___________
protein, peptide and catecholamine hormone
they are the primary receptors for the different steroid hormones?
Cytoplasm