Heme 1 Flashcards

1
Q

most common type of hemophilia in the US

A

hemophilia A

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2
Q

hemophilia A

A

x linked recessive disease that predominantly affects males who have only one x chromosome - caused by factor VIII deficiency

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3
Q

s/sx of hemophilia A
6

A

easy bruising
excessive bruising
bleeding into joints (hemarthrosis)
delayed bleeding or bleeding for several hours to days
heavy menses
hematuria

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4
Q

hemophilia A labs - aPTT, PT, fibrinogen, plts

A

aPTT is prolonged
normal - PT, fibrinogen, plts

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5
Q

hodgkin’s lymphoma

A

cancer of the beta lymphocytes (B cells)

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6
Q

cancer of the beta lymphocytes (B cells)

A

hodgkin’s lymphoma

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7
Q

hodgkin’s lymphoma s/sx
6

A

night sweats
fevers
pain w/ alocholic drinks
pruritis
painless enlarged lymph nodes (neck)
anorexia

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8
Q

hodgkin’s lymphoma is identified by the presence of what cells

A

Reed-Sternberg cells

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9
Q

multiple myeloma

A

cancer of the plasma cells

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10
Q

cancer of the plasma cells

A

multiple myeloma

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11
Q

multiple myeloma s/sx
6

A

fatigue
weakness
bone pain usually in back or chest
proteinuria
hypercalcemia
normocytic anemia

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12
Q

common meds that can cause neutropenia
7

A

psychotropics
antivirals
abx
NSAIDs
antithyroids
ACEIs
propanolol

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13
Q

non-hodgkin’s lymphoma

A

a group of metalogic malignancies that are derived from B cell progenitors, T cells progenitors, mature B cells, mature T cells, or natural killer cells

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14
Q

usually occurs in older adults >65, presents with night sweats, fever, weight loss, and painless lymphadenopathy

A

non-hodgkin’s lymphoma

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15
Q

gradual onset of symmetric peripheral neuropathy starting in the feet and/or arms

A

vitamin b12 deficiency

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16
Q

vitamin b12 def - cells are micro or macro

A

macro

17
Q

the proportion of RBCs in 1 mL of plasma

A

hct

18
Q

micro value

A

<80

19
Q

macro value

A

> 100

20
Q

average hgb content in a RBC

A

MCH

21
Q

the stored form of iron

A

serum ferritin

22
Q

most sensitive test for IDA

A

serum ferritin

23
Q

serum ferritin level - IDA

A

decreased

24
Q

serum ferritin level - thalasemmia

A

normal to high

25
Q

serum iron level - IDA

A

decreased

26
Q

serum iron level - thalassemia and macrocytic anemias

A

normal to high

27
Q

immature RBCs that still have their nuclei

A

reticulocytes

28
Q

gold standard test to dx hemoglobinopathies such as SCA, thalassemia, and more

A

hgb electrophoresis

29
Q

order what two labs when evaluating MCV >100

A

B12 and folate levels

30
Q

microcytic, hypochromic anemias
2

A

IDA
thalassemia

31
Q

B12 and folate def anemia size and color

A

macro, normo

32
Q

anemia of chronic disease MCV and MCH

A

normalcytice, normochromic

33
Q

SCA RBC normal life span

A

10-20 days

34
Q

SCA MCV and MCH

A

normocytic/normochromic