Hematology PANCE Flashcards

1
Q

what are the 2 components of RBC

A

heme (fe)

globin

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2
Q

how is iron stored

A

ferritin

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3
Q

what is the feritin level with Fe deficiency anemia

A

decreased

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4
Q

what is the feritin level with anemia of chronic disease

A

increased

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5
Q

what are the two types of anemia

A

intrinsic (inherited)

extrinsic ( acquired)

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6
Q

what anemia: HgbS

A
  • sickle cell
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7
Q

what anemia: episidic anemia associated with sulfa drugs fava beans and infections

A

G6PD deficiency

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8
Q

what is coobs +

A

autoimmune hemolytic anemia

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9
Q

what is the pentad with TTP

A
hemolytic anemia 
thrombocytopenia 
kidney damage 
neurologic 
fever
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10
Q

HUS triad

A
  • thrombocytopenia
  • hemolytic anemia
  • kidney damage
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11
Q

popcorn: rouleaux formation

A

multiple myeoloma

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12
Q

Popcorn: Howell Jolly bodies

A

sickle cell

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13
Q

popcorn anemia:

- target cells 2

A

sickle cell

thalassemia

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14
Q

popcorn anemia:

- spherocytes

A

heriditary spherocytosis

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15
Q

popcorn anemia

- hypersegmented neutrophils 2

A

B12

folate

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16
Q

popcorn Blood:

auer rods

A

AML

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17
Q

popcorn Blood:

reed sternberg

A

hodgkins lymphoma

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18
Q

what three things can cause anemia

A
  1. RBC loss
  2. RBC destruction
  3. Dec RBC production
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19
Q

what if there is anemia with decreased reticulocyte counts

A

that means the Bone marrow is not working well

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20
Q

what are the three microcytic anemia

A
  1. Fe deficincy
  2. lead
  3. thalassemia
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21
Q

what is the primary cause of normocytic anemia

A

anemia of chronic disease

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22
Q

what are the two macrocytic anemia

A

B12

Folate

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23
Q

what has neuro factors B 12 or folate

A

B 12

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24
Q

what do you have to look for when giving B12

A

hypokalemia

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25
Q

what is the + shillings test dx

A
  • pernicious anemia
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26
Q

ETOH causes what type of anemia

A

macrocytic

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27
Q

ringed sideroblast and basophilic stippling what anemia

A

Lead poisoning

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28
Q

what type of hemoblibin in a baby

A

F

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29
Q

Popcorn anemia: hair on end appearance X ray

A

Beta thalasemia

30
Q

what is the mC cause of G6pD crisis

A

infections

31
Q

what are the 2 tx for sickle cell crisis

A
  1. fluids

2. hydroxyuria

32
Q

how do you tx autoimmune hemolytic anemia

A
  • steroids
33
Q

what is the MCC of autoimmune hemolytic anemia

A

SLE

34
Q

what is the pentad with TTP

A
  1. thrombocytopenia
  2. hemolytic anemia
  3. kidney
  4. fever
  5. neuro symptoms
35
Q

what is the triad with HUS

A
  1. thrombocytopenia
  2. hemolytic anemia
  3. kidney
36
Q

adsams 13 is associated with what pathology

A

TTP

37
Q

HUS is assocated with what infection

A

HUS

38
Q

how do you treat TTP

A

steroids

39
Q

do you give HUS abx

A

no it will make them worse

40
Q

what type of condition is TTP

A

autoimmune

41
Q

How do you treat TTP and HUS

A

plasma phoresis

42
Q

what causes DIC

A

gram - infections

43
Q

how do you treat DIC

A

FFP

44
Q

what causes the increased bleeding with ITP

A

idiopathic

45
Q

isolated thrombocytopenia w/o splenomegaly

A

Idiopathic thrombocytopenia

46
Q

what do kids have prior to ITP

A

viral infection

47
Q

How is hemopehila A and B transfered

A

X linked recessive

48
Q

what bleeding pathology can be treated with desmopressin (2)

A

hemophilla 8

WVD

49
Q

what is the gold standard test for VWD

A

ristocetin

50
Q

what virus infection is associated with hogkins lymphma

A
  • EBV
51
Q

what is the clinical presentation for hogkins lymphoma

A

painless lympadenopathy

turns painful with ETOH

52
Q

“owl eye”

A

hogkins lymphoma

53
Q

what lymph nodes for hogkins lymphoma

A

cervical and supraclavicular

54
Q

what may you see on a chest CT with hogkins lymphoma

A

mediastinal lymphadenopathy

55
Q

what lymph nodes for non hodgkins lymphoma

A

peripherial

56
Q

Birket lymphoma is associated with what type of lymphoma

A

non hodgkins

57
Q

“stary night on blood smere”

A

Birket lymphoma

58
Q

How do you tx multiple myoloma

A

stem cell transplant

59
Q

“M spike”

“bence jones protein”

A

multiple myoloma

60
Q

what is the most common leukemia in adults

A

CLL

61
Q

what are the three myeloid cells

A
  • RBC
  • WBC
  • platelets
62
Q

what condition is an increase in all three myeloid cells

A

polycythemia vera

63
Q

puritis after a hot bath

A

PV

64
Q

how do you tx PV

A
  • phlebotomy

- hydroxyurea

65
Q

increased hematocrit as a response to another process (COPD)

A

secondary erythrocytosis

66
Q

what are the three conditions that may cause you to clot more

A
  • factor V leiden mutation
  • protein C deficiency
  • antithrombin III dificiency
67
Q
  • blueberry muffin rash
  • hepato spleno megaly
  • hearing loss
  • mental retardation
A

toxoplasmosis

68
Q

what CD4 count for toxoplasmosis

A

100

69
Q

what is the tx for toxoplasmosis

A

sulfadiazadine + pyrimetherine

70
Q

MRI: ring enchnacing lesions

A

toxoplasmosis

71
Q

how do you tx enterobiasis (pin worm)

A
  • albendazole