ER EOR Hematology Flashcards
what is the MC leukemia in Kids
ALL
what chromosome abmormality is associated with ALL
Downs
what is the MC symptom of ALL
fever
what is the CBC on ALL
pancytopenia
what are the the PE findings with ALL
hepatosplenomegaly and lymphadenopathy
who PE findings for AML
splenomegaly and gingival hyperplesia
auer rods on smere
AML
what is are you thinking when you see WBC < 5 > 100
leukenia
when PE finding seems to be consistent with all of the leukenias
splenomegaly
what is the philidalphia chromosome associated with
CML
what is the MC leukenia in adults
CLL
what is pathopneumonic for CLL
smudge cells
what type of lymphoma is associated with non hidgkins
birkett lymphoma
what is reed sternberg cells associated with
hodgkins lymphoma
what virus is associated with hogkins lymphoma
EBV
fever, night sweats, weight loss think what
hogkins lymphoma
painless lympahdenopathy (pathology)
lymphoma
what lymphoma is associated with extranodal spread
non hodgkins
what type of osteomyelitis with sickle cell
salmonella
aplatic crisis with sicke cell what virus
parvo B 19
what penis issue is associated with sickle cell
priapism
howell jonny bodies associated with what disorder
sickle cell
what are the three tx for sickle cell
- fluids
- O2
- hydroxy uria
what are the three hypercoaguable conditions in pance prep
- factor V leiden
- protein C deficiency
- antithrombin III deficiency
how do you tx hercoag disoredrs
anticoag (warfarin, Xa)
what type of anemias have schistocytes
hemolytic
what type of bilirubin does hemolytic anemias have
indirect bilirubin
what is coombs test -
heriditary spherocytosis
what is coombs +
autoimmune hemolytic anemia
what anemias have normal coags
TTP + HUS
TTP or HUS Kids
HUS
Bite cells what two pathologies
thalasemia
G6PD deficienecy
hypersegmented neutrophils what two pathologies
- B 12
- Folate
target cell what two
sickle cell
thalathemia
what causes anemia
- blood loss
- blood destruction
- RBC production
what are the 3 micocyticanemia
- iron deficiency
- lead
- thalassemia
what is the primary normocytic anemia
- anemia of chronic dz
what are the two macrocytic anemias
B12
Folate
what type of anemia has neurologic symptoms
B12
if you give B12 what do you need to watch for
hypokalemia
auto ammune distruction loss of perietal cells that secrete IF
pernitious anemia
what are 4 causes of B12 defienency
Pernitions anemia
celiac
ETOH
vegans
what Vit increases iron absorbtion
C
How do you tx ITP 2
Kids: observation
adults: steroids
how do you Tx TTP 2
plasmapharesis, steroids
how do you tx hemophilia A
desmopression
how do you tx factor hemophilia A
factor 9 infusion
what hemophilia is deep tissue
hemophilla A
polycyemia vera
increase in all 3 myeloid cells
Hoe to tx PV
phlebotomy
pruitis after the shower
PV
