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Pharmacology > Hemat > Flashcards

Hemat Flashcards

1
Q

Anti dyslipidemic drugs

A

Statins
Intestinal cholesterol absorption inhibitors
Fibrates
Bile acid binding agents
Niacin

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2
Q

Statins

A

Atorvastatin
Rosuvastatin
Fluvastatin
Pitavastatin
Pravastatin
Simvastatin
Cerivastatin

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3
Q

Which drugs group has max ldl lowering potential

A

Statins

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4
Q

Which statins can be given all day

A

Atorvastatin
Rosuvastatin

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5
Q

Longest acting statin

A

Rosuvastatin

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6
Q

Adverse effects of statins

A

Myopathy,
Hepatotoxicity
Hyperglycemia

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7
Q

Uses of statins

A

Pleitropic
Plaque stabilization
Dec endothelial dysfunction
Dec inflammation
Dec oxidative stress
Dec thrombosis

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8
Q

Intestinal cholesterol absorption inhibitor

A

Ezetimibe- inhibits npl1c1
Combined with statins to prevent tolerance

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9
Q

Fibrates

A

Clofibrate
Fenifibrate
Bezafibrate
Gemfibrozil

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10
Q

Drug grp having max tg lowering potential

A

Fibrates- act by ppar alpha stimulation- inc lipoprtn lipase- lower tg

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11
Q

Side effects of fibrates

A

Inc risk of gall stones
Gemfibrozil- myopathy

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12
Q

Baba

A

Cholestyramine
Cholestipol
Cholesevelam

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13
Q

Doc in dyslipidemic children nd preg

A

Baba

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14
Q

Max hdl increasing potential

A

Vit b3 - niacin

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15
Q

Side effects of niacin

A

Flushing, itching- laropiprant
Hyperuricemia
Hepatotoxicity
Insulin resistance

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16
Q

Drugs affecting blood flow- anti platelets

A

Anti platelets-
TXA2 inhibitors
Adp receptor inhibitors
Drigs acting on gpllb/llla
Drugs acting on thrombin receptors

17
Q

Anti fibrin/ anti coagulants

A

Oral anti coagulants- vit k inhibitors
Direct thrombin inhibitors
Factor Xa inhibitor

Injectable anti coagulants-
Indirect thrombin inhibitor- heparin
Direct thrombin inhibitor

18
Q

Thrombolytic/ fibrinolytic drugs

A

Surat
Streptokinase
Urokinase
Reteplase
Alteplase
Tenecteplase

19
Q

Drugs affecting blood cells

A

Hematinics
Growth factors

20
Q

Hematinics

A

Iron
Folic acid
Vit b12

21
Q

Iron therapy

A

Oral iron-
Ferrous sulphate, ferrous fumarate

Inj iron- iron dextran- iv as well as im
Iron sorbitolcitrate
By z tract technique

22
Q

Folica acid dose

A

400 microgram
4000 in anti epileptic therapy

23
Q

Hematipoietic growth factors

A

Rbc- erythropoietin
Wbc- G- CSF, GM- CSF
Platelets- IL- 11, Thrombopoietin

24
Q

Hematopoietic growth factor drugs

A

Erythropoietin- darbopoietin
G csf- filgrastim, peg filgrastim
Gm csf- sargramostim
Molgramostim

IL 11- oprelevikin

Pharmacology (18 decks)

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