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1
Q

90 percent aq humour drainage occurs by

A

Iridiocorneal angle - trabercular outflow

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2
Q

10percent aq humour drainage

A

Uveoscleral outflow

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3
Q

Diff btw close angle and open angle glaucoma

A

Open angle- decreased potency of trabercular outflow
Closed angle - iridiocorneal angle closed due to mydriatics

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4
Q

Doc for acute congestive glaucoma

A

Mannitol

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5
Q

Acute open angle glaucoma doc

A

Pgf2 alpha analogs

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6
Q

Pgf2 alpha analogs

A

Latanoprost
Bimatoprost
Tranoprost

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7
Q

S/e of pgf2 alpha analogs

A

Sandy eyes
Orbital fat atrophy
Anteri uveitis
Cystoid macular edema
Heterochromia iridis
Hypertrichosis

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8
Q

B blockers in glaucoma

A

Non selective- TLC- timolol, levobunolol, cartelol

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9
Q

S/E of beta blockers

A

ABCD- Allergic blepharoconjunctivities
Bleapharospasm
Corneal hypothesis
Dry eyes

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10
Q

Miotics-

A

Pilocarpine, physostigmine, carbachol

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11
Q

S/E of miotics

A

CR- Ciliary muscle spasm
Cataract
Constrict pupil
Retinal detachment

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12
Q

Alpha agonist in glaucoma

A

Dipivefrine- epinephrine
Apraclonidine, brimonidine

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13
Q

Carbonic anhydrase inhibitors-

A

Systemic-
Acetazolamide
Methazolamide
Topical- brinzolamide
Dorzolamide

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14
Q

S/e of carb anhydrase inhibitors

A

Sulfa allergy- bm supression
Paraesthesia
Tingling
Ciliary edema

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15
Q

Doc phaeochromocytoma

A

Metyrosine

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16
Q

Release of CA inhibited by

A

Guanethidine
Bretylium

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17
Q

CA reuptake inhibitors

A

Cocaine
Anti depressants

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18
Q

Symp receptors

A

Alpha1 - Gq
Alpha 2 - Gi
Beta 1,2,3- Gs

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19
Q

Beta 1 receptors prsnt in

A

Heart, jg cells of kidney

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20
Q

Beta 2 receptors prsnt in

A

Skeletal muscle smooth muscle, liver

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21
Q

Beta 3 receptors present in

A

Adipose tissue, bladder

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22
Q

Doc for cardiogenic shock

A

Nor epinephrine

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23
Q

Doc for vasodilatory shock

A

Nor epinephrine

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24
Q

Nor epinephrine does not act on which sympathetic receptor

A

Beta 2

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25
Doc in oliguria
Dopamine in low doses
26
Dopamine in high dose acts on which sympathetic receptor
Alpha 1
27
Synthetic CAs
Dobutamine- beta 1 Isoprenaline- beta1,2,3 Fenoldopam Ibopamine
28
Doc in sp. Anesthesia and aortic dissection
Phenylephrine
29
Doc for postural hypotension
Midodrine
30
Nasal decongestants
Drops- oxymetazoline Xylometazoline Naphazoline Phenylephrine Tablets- phenylephrine Ephedrine Pseudoephedrine
31
Bronchodilators
Salbutamol Salmeterol Fometerol
32
Tocolytics
Ritodrine Isosuprine Atosiban Amlodipine Nifedipine Nsaids Halothane
33
Doc of narcolepsy and obstructive sleep apnea
Modafinil
34
Doc for ADHD
Amphetmines- methyl phenidate Dextroamphetamine Methyl amphetamine Lisdextro amphetamine
35
Doc for amphetamine toxicity
Ammonium chloride, chlorpromazine
36
Cheese reaction cause and doc
Tyramine taken with mao inhibitors Phentolamine
37
Doc for hypotension in pregnancy
Ephedrine
38
Approved anti obesity drugs
Mephentermine+ topiramate Bupropion+ zonisamide Liraglutide+ semaglutide Orlistat+ cetlistat Olestra
39
Vasomotor reversal of dale
Alpha blockers + epinephrine = unopposed fall in bp
40
Alpha 2 a agonists
CDTAG- clonidine Dexmeditomidine Tizanidine Alpha methydopa Guanfacine, guanbenz
41
Diagnosis of phaeochromocytoma
Clonidine, phentolamine
42
Uses of clonidine
Post menopausal hot flushes Hypertension Control, withdrawal of smoking Diabetic diarrhoea Epidural analgesic Migraine prophylaxis ADHD Gilles de tourette syndrome
43
Side effects of clonidine
HADSE- hypotension Apnea in kids Dry eyes, mouth Sedation Erectile dysfunction
44
Doc for hypertensive crisis
Phentolamine
45
Doc for chronic hypertension in pregnancy
Labetolol
46
Doc for preeclapsia- pregnancy induced hypertension
Labetolol
47
Side effects of alpha methyldopa
Depression Dle Damaged rbc
48
Doc for hypertension in phaeochromocytoma
Phenoxynenzine
49
Cheese reaction doc
Phentolamine
50
Doc for angiography
Tolazoline
51
Doc for hypertension
Prazosin
52
Tt of scorpion sting
Tetrazosin
53
Selective alpha blockers
Prazosin Tetrazosin Doxazosin Afluzosin
54
Doc for bph
Tamsulosin Silodosin
55
Selective alpha 2 blocker
Yohimbine Idoxazan
56
Beta blocker types
First gen- non selective 2nd gen - cardioselective 3rd gen- vasodilators
57
Non selective beta blockers
Pyari teri NS Propanolol Pindolol Penbutolol Timolol Nadolol Sotalol
58
Cardioselective beta 1 blockers
BEAAM Bisoprolol Esmolol Acebutolol Atenolol Metoprolol
59
Non selective Vasodilators
CLuB Cartelol Carvedilol Labetalol Bucindolol
60
Cardioselective vasodilators
Canara bank Celiprolol Nebivolol Betaxolol
61
Longest acting beta blocker
Nadolol
62
Shortest acting beta blocker
Esmolol
63
Most lipid soluble beta blocker
Propanolol
64
Least lipid soluble beta blocker
Atenolol
65
Most cardioselective beta blocker
Nebivolol
66
Beta blocker with cardioprotective action
Carvedilol Nebivolol
67
Uses of beta blockers
Prophylaxis of migraine Portal hypertension Performance anxiety Phaeochromocytoma Hemangioma Essential tremors Akathesia Thyroid storm
68
Doc for beta blocker toxicity
Glucagon
69
Four lines of t/t of Myasthenia Gravis
1. Neostigmine + atropine 2. Plasmapheresis 3. Immunosupressants 4. Thymectomy

Pharmacology (18 decks)

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