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Pharmacology > Ans > Flashcards

Ans Flashcards

1
Q

90 percent aq humour drainage occurs by

A

Iridiocorneal angle - trabercular outflow

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2
Q

10percent aq humour drainage

A

Uveoscleral outflow

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3
Q

Diff btw close angle and open angle glaucoma

A

Open angle- decreased potency of trabercular outflow
Closed angle - iridiocorneal angle closed due to mydriatics

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4
Q

Doc for acute congestive glaucoma

A

Mannitol

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5
Q

Acute open angle glaucoma doc

A

Pgf2 alpha analogs

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6
Q

Pgf2 alpha analogs

A

Latanoprost
Bimatoprost
Tranoprost

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7
Q

S/e of pgf2 alpha analogs

A

Sandy eyes
Orbital fat atrophy
Anteri uveitis
Cystoid macular edema
Heterochromia iridis
Hypertrichosis

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8
Q

B blockers in glaucoma

A

Non selective- TLC- timolol, levobunolol, cartelol

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9
Q

S/E of beta blockers

A

ABCD- Allergic blepharoconjunctivities
Bleapharospasm
Corneal hypothesis
Dry eyes

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10
Q

Miotics-

A

Pilocarpine, physostigmine, carbachol

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11
Q

S/E of miotics

A

CR- Ciliary muscle spasm
Cataract
Constrict pupil
Retinal detachment

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12
Q

Alpha agonist in glaucoma

A

Dipivefrine- epinephrine
Apraclonidine, brimonidine

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13
Q

Carbonic anhydrase inhibitors-

A

Systemic-
Acetazolamide
Methazolamide
Topical- brinzolamide
Dorzolamide

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14
Q

S/e of carb anhydrase inhibitors

A

Sulfa allergy- bm supression
Paraesthesia
Tingling
Ciliary edema

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15
Q

Doc phaeochromocytoma

A

Metyrosine

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16
Q

Release of CA inhibited by

A

Guanethidine
Bretylium

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17
Q

CA reuptake inhibitors

A

Cocaine
Anti depressants

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18
Q

Symp receptors

A

Alpha1 - Gq
Alpha 2 - Gi
Beta 1,2,3- Gs

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19
Q

Beta 1 receptors prsnt in

A

Heart, jg cells of kidney

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20
Q

Beta 2 receptors prsnt in

A

Skeletal muscle smooth muscle, liver

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21
Q

Beta 3 receptors present in

A

Adipose tissue, bladder

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22
Q

Doc for cardiogenic shock

A

Nor epinephrine

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23
Q

Doc for vasodilatory shock

A

Nor epinephrine

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24
Q

Nor epinephrine does not act on which sympathetic receptor

A

Beta 2

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25
Q

Doc in oliguria

A

Dopamine in low doses

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26
Q

Dopamine in high dose acts on which sympathetic receptor

A

Alpha 1

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27
Q

Synthetic CAs

A

Dobutamine- beta 1
Isoprenaline- beta1,2,3
Fenoldopam
Ibopamine

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28
Q

Doc in sp. Anesthesia and aortic dissection

A

Phenylephrine

29
Q

Doc for postural hypotension

A

Midodrine

30
Q

Nasal decongestants

A

Drops- oxymetazoline
Xylometazoline
Naphazoline
Phenylephrine
Tablets- phenylephrine
Ephedrine
Pseudoephedrine

31
Q

Bronchodilators

A

Salbutamol
Salmeterol
Fometerol

32
Q

Tocolytics

A

Ritodrine
Isosuprine
Atosiban
Amlodipine
Nifedipine
Nsaids
Halothane

33
Q

Doc of narcolepsy and obstructive sleep apnea

A

Modafinil

34
Q

Doc for ADHD

A

Amphetmines- methyl phenidate
Dextroamphetamine
Methyl amphetamine
Lisdextro amphetamine

35
Q

Doc for amphetamine toxicity

A

Ammonium chloride, chlorpromazine

36
Q

Cheese reaction cause and doc

A

Tyramine taken with mao inhibitors
Phentolamine

37
Q

Doc for hypotension in pregnancy

A

Ephedrine

38
Q

Approved anti obesity drugs

A

Mephentermine+ topiramate
Bupropion+ zonisamide
Liraglutide+ semaglutide
Orlistat+ cetlistat
Olestra

39
Q

Vasomotor reversal of dale

A

Alpha blockers + epinephrine = unopposed fall in bp

40
Q

Alpha 2 a agonists

A

CDTAG- clonidine
Dexmeditomidine
Tizanidine
Alpha methydopa
Guanfacine, guanbenz

41
Q

Diagnosis of phaeochromocytoma

A

Clonidine, phentolamine

42
Q

Uses of clonidine

A

Post menopausal hot flushes
Hypertension
Control, withdrawal of smoking
Diabetic diarrhoea
Epidural analgesic
Migraine prophylaxis
ADHD
Gilles de tourette syndrome

43
Q

Side effects of clonidine

A

HADSE- hypotension
Apnea in kids
Dry eyes, mouth
Sedation
Erectile dysfunction

44
Q

Doc for hypertensive crisis

A

Phentolamine

45
Q

Doc for chronic hypertension in pregnancy

A

Labetolol

46
Q

Doc for preeclapsia- pregnancy induced hypertension

A

Labetolol

47
Q

Side effects of alpha methyldopa

A

Depression
Dle
Damaged rbc

48
Q

Doc for hypertension in phaeochromocytoma

A

Phenoxynenzine

49
Q

Cheese reaction doc

A

Phentolamine

50
Q

Doc for angiography

A

Tolazoline

51
Q

Doc for hypertension

A

Prazosin

52
Q

Tt of scorpion sting

A

Tetrazosin

53
Q

Selective alpha blockers

A

Prazosin
Tetrazosin
Doxazosin
Afluzosin

54
Q

Doc for bph

A

Tamsulosin
Silodosin

55
Q

Selective alpha 2 blocker

A

Yohimbine
Idoxazan

56
Q

Beta blocker types

A

First gen- non selective
2nd gen - cardioselective
3rd gen- vasodilators

57
Q

Non selective beta blockers

A

Pyari teri NS
Propanolol
Pindolol
Penbutolol
Timolol
Nadolol
Sotalol

58
Q

Cardioselective beta 1 blockers

A

BEAAM
Bisoprolol
Esmolol
Acebutolol
Atenolol
Metoprolol

59
Q

Non selective Vasodilators

A

CLuB
Cartelol
Carvedilol
Labetalol
Bucindolol

60
Q

Cardioselective vasodilators

A

Canara bank
Celiprolol
Nebivolol
Betaxolol

61
Q

Longest acting beta blocker

A

Nadolol

62
Q

Shortest acting beta blocker

A

Esmolol

63
Q

Most lipid soluble beta blocker

A

Propanolol

64
Q

Least lipid soluble beta blocker

A

Atenolol

65
Q

Most cardioselective beta blocker

A

Nebivolol

66
Q

Beta blocker with cardioprotective action

A

Carvedilol
Nebivolol

67
Q

Uses of beta blockers

A

Prophylaxis of migraine
Portal hypertension
Performance anxiety
Phaeochromocytoma
Hemangioma
Essential tremors
Akathesia
Thyroid storm

68
Q

Doc for beta blocker toxicity

A

Glucagon

69
Q

Four lines of t/t of Myasthenia Gravis

A
  1. Neostigmine + atropine
  2. Plasmapheresis
  3. Immunosupressants
  4. Thymectomy

Pharmacology (18 decks)

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