Heart Failure Drugs Flashcards

1
Q

digoxin

A

IV/PO

  • MOA: positive inotrope (CO), negative chronotrope (HR and workload) and dromotrope (excitability)
  • indication: HF and dysrhythmia
  • watch for toxicity
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2
Q

milrinone

A

IV gtt only

  • indication: 48-72 Hr manage acute exacerbation HF and end-stage HF (unresponsive to medication)
  • MOA: positive inotrope (CO), arteriodilator (decrease BP and workload)
  • SE: heart effects
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3
Q

dopamine

A
  • MOA: nonspecific, increase HR, vasoconstriction

- IV gtt in central line

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4
Q

dobutamine

A
  • MOA: beta1 agonist, postive inotrope and chronotrope
  • IV gtt in peripheral IV
  • AE: heart, brain
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5
Q

nitrates

A
  • MOA: vasodilator (increase O2 supply, decrease demand)
  • indication: coronary artery dilation, systemic vasodilation
  • SL, IV gtt, ointment/transdermal patch, PO
  • SE: heart, brain
  • contraindication: glaucoma, traumatic brain injury
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6
Q

antianginal (nitro)

A
  • SL/translingual spray: nitroglycerin (0.4 mg q5min)
  • PO: isosorbide mononitrate, isosobide dinitrate
  • topical: nitropaste
  • IV: nitroglycerin
  • nitroglycerin indication: acute severe angina, HF
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7
Q

antianginal (beta blocker)

A

IV/PO

  • lol
  • indication: angina/MI, dysrhythmia, HTN, HF
  • MOA: decrease BP, negative chronotrope (HR) and dromotrope (excitability)
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8
Q

CCB (-dipine)

A

indication: HTN, HF, angina

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9
Q

Dysthrhythmia Pharmacotherapy (DP)

A
  • SE: heart, brain, physical, genital
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10
Q

DP Na-channel blocker

A
  • procainamide, flecainide
  • anticholinergic symptoms
  • lupus symptoms
  • low blood cells (CBC)
  • paresthesia, seizure, dysrhythmias
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11
Q

DP K-channel blocker

A
  • amidarone, sotalol
  • monitor for HF, pulmonary edema
  • monitor for brady-dysrhythmia
  • photophobia
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12
Q

DP calcium-channel blocker (only work on heart)

A
  • diltiazem, verapamil
  • indication: tachy-dysrhythmia
  • SE: peripheral edema, fall, renal panel, I/O, hold med call provider (decrease BP)
  • may cause ventricular dysrhythmia
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