HEALING FUND HIGH YIELD

Question 1

what are the 4 stages of wound healing?

Answer 1

hemostasis
inflammation
proliferation or granulation
remodeling or maturation

Question 2

what are the three phases of tissue healing?

Answer 2

inflammatory- response phase
fibroblastic- repair phase
maturation- remodeling phase

Question 3

this phase is characterized by redness, swelling, tenderness, and temperature

Answer 3

response phase, inflammatory, phase II

Question 4

what reaction and mediators are released during the response phase, inflammatory or phase II? other events that happen here

why aren’t NSAIDs recommended?

Answer 4

vascular reaction

histamine, leukotrienes and cytokines

formation of clot

chronic inflammation

last 2-4 days

*inhibit inflammatory response delaying the healing process but they assist with pain and swelling

Question 5

this phase of the healing process begins within the 1st few hours and lasts 4-6 weeks

signs and symptoms of inflammatory phase subside

increased O2 and blood flow deliver nutrients

Answer 5

fibroblastic repair phase, phase III

Question 6

break down of fibrin clot forms connective tissue called _____?

Answer 6

granulation tissue that consists of fibroblast, collagen, and capillaries

Question 7

which type is found in the fibroblastic repair phase?

Answer 7

type I collagen

Question 8

what are the mechanical properties of collagen?

Answer 8

elasticity
viscoelasticity
plasticity

Question 9

this mechanical property has the capability to recover normal length after elongation?

Answer 9

elasticity

Question 10

this mechanical property allows the slow return to normal length and shape after deformation

Answer 10

viscoelasticity

Question 11

this mechanical property allows permanent change and deformation

Answer 11

plasticity

Question 12

what are the factors that impede healing?

Answer 12

extent of injury
edema
hemorrhage
poor vascular supply
separation of tissue
traction
atrophy
corticosteroids
keloids
infection
health

Question 13

what are the benefits of ligaments?

Answer 13

stability to joint
provide control
provide proprioceptive input or sense of joint position through mechanoreceptors
-3 grades of lig tears

Question 14

what are the factors that affect ligament sprains?

Answer 14

surgery or nonsurgical, generally do not last over time

immobilization, decreases tensile strength over long periods of time but provides stability through strengthening and increased muscle strength

Question 15

what are limiting variables of cartilage?

Answer 15

healing

Question 16

how does fibrocartilage/menisci heal?

Answer 16

depends on where

3 zones of various vascularity, so the greater the blood supply, the increase chance of healing

Question 17

what cleans up debris for the healing process of muscle?

Answer 17

hemorrhage and edema, phagocytosis

myoblastic cells

Question 18

what are the tendon limitations in the healing process?

Answer 18

not as vascular as muscle

• abundance of collagen needed
• collagen synthesis can be excessive resulting in fibrosis
• -reduced tensile strength thus contraction can pull tendons apart

Question 19

what is the limitation in nerve healing?

Answer 19

specialized and cannot regenerative once dead

Question 20

can peripheral nerves regenerate?

Answer 20

they if injury does not affect the cell body

Question 21

what is the regenerative time for nerves?

affect of scar formation?

Answer 21

3-4 mm/day, CNS regeneration is poor because they lack both connective sheath and proliferation

axon regeneration obstructed