Granulation Tissue Vs. Granulomatous Tissue

Question 1

Is the tissue that repairs wounds

Answer 1

granulation tissue

Question 2

Describe granulation tissue:

Answer 2

It is highly vascular and when viewed with the naked eye is red and granular

Question 3

In granulation tissue, what serves as the scaffolding for endothelial cells and fibroblasts that grow into the clot from the wound margin?

Answer 3

fibrin strands

Question 4

In granulation tissue, the wound fills with a blood clot and the fibrin strands in the clot serve as scaffolding for ___ and ____ that grow into the clot from the wound margin.

Answer 4

endothelial cells & fibroblasts

Question 5

In granulation tissue, endothelium forms new ____ and fibroblasts makes new ___ that restores ___

Answer 5

vascular channels; collagen; tensile strength

Question 6

What are the two main cell types in granulation tissue?

Answer 6

1. endothelial cells
2. fibroblasts

Question 7

What is the terminal event in injury/inflammatory lesion?

Answer 7

repair

Question 8

What would happen to wounds with out granulation tissue?

Answer 8

wounds would not heal

Question 9

Granulation tissue may overgrow and form an unwelcome mass called a:

Answer 9

pyogenic granuloma

Question 10

A pyogenic granuloma can simply be considered:

Answer 10

granulation tissue (too much of a good thing)

Question 11

An abscessed tooth left untreated may develop a mass of chronically inflamed granulation tissue at the root tip called a:

Answer 11

periapical dental granuloma

Question 12

This is a photo of ____. What do the red areas represent?

Answer 12

granulation tissue; newly formed vascular channels

Question 13

This image shows a ____, which is an overgrowth of ____.

Answer 13

pyogenic granuloma; inflamed granulation tissue

Question 14

A persistent growth of inflamed granulation tissue at the apex of a tooth with a necrotic pulp:

Answer 14

periapical dental granuloma

Question 15

Tissue that contains granulomas:

Answer 15

granulomatous tissue

Question 16

A collection of macrophages, a few lymphocytes, and a surrounding this collar of fibroblasts:

Answer 16

granuloma

Question 17

macrophages in a granuloma may also be called:

Answer 17

epihtelioid histiocytes

Question 18

Granulomas may or may not have:

Answer 18

multinucleated giant cells

Question 19

In granulomatous tissue, if nuclei are arranged in a radial pattern (horseshoe or necklace), it is a:

Answer 19

Langhan’s Giant Cell

Question 20

In granulomatous tissue, if nuclei are randomly arranged in the cytoplasm, this is a:

Answer 20

foreign body type giant cell

Question 21

Most injuries and infections provoke ____, a vascular response that displays the cardinal signs of inflammation (rubor, calor, dolor, and tumor)

Answer 21

exudative inflammation

Question 22

A limited group of noxious agents (microbes and foreign material) do not provoke ____ but instead they cause the formation of ____.

Answer 22

exudative inflammation; granulomas

Question 23

A limited group of noxious agents (microbes and foreign material) do not provoke exudative inflammation but instead they cause the formation of granulomas and this response is known as;

Answer 23

granulomatous inflammation

Question 24

Lacking redness, swelling, and pain, _____ are always chronic and may be silent for weeks to months before symptoms arise.

Answer 24

granulomatous diseases

Question 25

_____ is the mother of all infectious granulomatous diseases; ___ is another example.

Answer 25

tuberculosis; leprosy

Question 26

In tuberculosis, the granulomas characteristically exhibit a pattern of necrosis referred to as ____ , therefore the term ____.

Answer 26

caseous (cheese-like) necrosis; caseating granulomas

Question 27

What can be seen in this high-power image? How do you know?

Answer 27

langhan’s giant cell; radial (horseshoe) arrangement of nuclei

Question 28

What can be seen in this medium-power image? How do you know?

Answer 28

several foreign body giant cells; random arrangement of nuclei in cytoplasm

Question 29

A focal collection of epithelioid histiocytes with a sprinkling of lymphocytes, maybe one or more multinucleated giant cells and a thin collar of fibroblasts surrounding them all:

Answer 29

granuloma