GI Microbiome Flashcards
What is the microbiome?
What is the microbiota?
What is the ratio of human cells in our bodies to bacterial cells in our bodies?
1:1
Microbiota consists of more than bacteria so the ratio of microbiota : our cells is higher, but just bacteria to us is close to 1:1
What is the human holobiont?
The biologic entity consisty of human and microbial cells that function together in elaborate symbiosis
What are the two types of symbiosis?
How does your microbiota develop when you’re in utero and as a young child?
What impact does diet have on the microbiota?
How do environment, circadian rhythm, and medication use influence our microbiota?
What are the general things that microbiota do for our bodies?
How do our microbiota play a role in metabolism and biosynthesis?
Biosynthesis: Derive their nutrition from nutrients we ingest as well as our own cells and mucin. They metabolize toxins, xenobiotics, fiber and bile salts for us. They also produce vitamins K and B12, steroid hormones, neurotransmitters and short chain fatty acids.
Metabolism: see slide for what the SCFAs from microbiota do
How do our microbiota play a role in bacterial interference?
What role do microbiota play in immunity?
How is the microbiota involved in inflammation?
What is dysbiosis?
What are options that can be used to treat dysbiosis?
What are prebiotics? What are probiotics?
What are some of the issues with probiotics? Pros and Cons?
What is the procedure for doing fecal microbiota transplant? What are some of the pros and cons?
