GI Medicine 9 - Specific GI Presentations

Question 1

List the two broad catagories of causes of upper GI haemorrhage.

Answer 1

Coagulopathy
GI Pathology

Question 2

List three pertinent historical questions in cases of upper GI haemorrhage.

Answer 2

Prior history of bleeding diatheses.
Any evidence of nasal, oral or pulmonary disease
Previous GI signs?

Question 3

List three causes of GI pathology causing upper GI haemorrhage.

Answer 3

Hypoadrenocorticism
NSAIDs
Gastric carcinoma

Question 4

List two possible complications of gastric ulcers.

Answer 4

Chronic (external) blood loss -> iron deficiency
Perforation -> septic peritonitis

Question 5

List three parts of gastric ulcer therapy

Answer 5

Omeprazole
Sucralfate
Analgesia

Question 6

List three parts of the treatment of eosinophilic enteritis.

Answer 6

Anthelmintic therapy
Dietary trial
+/- steroids

Question 7

List three causes of hypoalbuminaemia

Answer 7

Liver disease - bile acid stimulation test
Intestinal disease - PLE
Kidney (glomerular) disease - PLN

Question 8

List two complications of hypoalbuminaemia

Answer 8

Effusions (pure transudate)
Pre-disposition to thrombi formation (hypercoagulable)

Question 9

List three differential diagnoses for protein losing enteropathy

Answer 9

IBD
Lymphagiectasia
Alimentary lymph(sarco)ma

Question 10

What is the main class of drug used for the treatment of lymphoplasmocytic colitis and how do they work?

Answer 10

5-ASA derivatives
Sulfonamide bound to 5-ASA, cleaved by colonic bacteria and allowing the release of 5-ASA, which is a local anti-inflammatory

Question 11

Which drug is contraindicated in small intestinal disease?

Answer 11

Sulphsalazine

Question 12

What is a major side effect of 5-ASA derivatives (sulphalazine)?

Answer 12

Kerato-conjunctivitis sicca

Question 13

What is the main clinical signs of a rectal polyp?

Answer 13

Haematochezia WITHOUT diarrhoea

Question 14

Which breeds of dogs a predisposed to granulomatous colitis?

Answer 14

Young boxers, french bulldogs

Question 15

What are the clinical signs of granulomatous colitis?

Answer 15

Large intestinal diarrhoea and severe weightloss

Question 16

How would you treat granulomatous colitis in young boxers/french bulldogs?

Answer 16

Eradication of E.coli and clinical remission with enrofloxacin.
5mg/kg PO SID for 6-8 weeks and 1 month beyond clinical resolution