Gastroenterology Flashcards
what takes place in the gut?
digestion/absorption of nutrients stomach - alcohol and water duodenum - iron and B12 jejunum - folate large intestine - water
what takes place in the pancreas?
exocrine portion - production of enzymes to digest food
endocrine - production of insulin
what takes place in the gall bladder?
concentration/storgae of bile
fat digestion and absorption
what takes place in the liver?
metabolism of nutrients and toxins
production of bile
protein synthesis
GI symptoms?
pain - localised/referred dysphagia dyspepsia - discomfort of upper tract nausea/vomitting diarrhoea constipation steatorrhoea bleeding - haemaemesis, melanea - upper and lower tract weight loss
investigations for upper GI tract?
endoscopy
investigations for lower GI tract?
sigmoidoscopy
colonoscopy
radiographs show?
plain
contrast - caused by barium swallow, meal, enema
ultrasound taken to look at?
especially biliary tract, liver
MRI taken to look at?
biliary tract, liver, pancreas
gut
antacids suppress acid - what are examples of antacids?
aluminium hydroxide
calcium carbonate - rennie
aligante based - gaviscon
gastric acid reduction caused by?
histamine receptor antagonists - H2 blockers
ranitidine, cimetidine
PPI’s - omeprazole, lansoprazole
when do you treat the CNS with anti emetics? and what are some examples?
when there is chemical stimulation of the vomitting centre treat the CNS
domperidone
metoclopramide ondasteron
when to treat the gut? with what?
distension of the gut is causing sickness
anti histamines - cyclizine
ondansetron - serotonin antagonist
what is GORD?
gastro oseophageal reflux disease
excess acid at oseophageal sphinctor
= loss of tone
delayed gastric emptying
what is GORD associated with?
associated with obesity
lying flat
fatty foods
smoking
gord symptoms?
diagnosed by?
heart burn
endoscopy
how to treat gord?
lifestyle
drugs - antacids, PPI’s
rarely surgery
complications caused by GORD?
stricture formation
cancer - via barretts oseophagus
what is peptic ulcer disease?
gastric/duodenal - gastric can become malignant
15-20% of population affected, more in elderly and men
caused by helicopter pylori
NSAIDS - esp gastric
symptoms of peptic ulcer disease?
epigastric pain
dyspepsia
vomitting
anorexia
complications from peptic ulcers?
bleeding - haematemesis, malaena
perforation
investigations for peptic ulcers?
endoscopy
biopsy if gastric
H.pylori - biopsy, breath test, serology