Addiciton Flashcards
1
Q
what are some signs of drug dependence?
A
increasing tolerance physiological withdrawal state on cessation use of drug to avoid withdrawl strong desire/compulsion to use progressive neglect of other interests keeps using despite awareness of damage
2
Q
what is the neuroscience behind dependence?
A
increased dopamine activity in mesolimbic system causes dependence
3
Q
what are the 4 L’s
A
liver
love
livelihood
law
4
Q
deaths from dependence caused by?
A
accidents/injury
liver disease
cardiovascular disease
cancers
5
Q
what is the first phase of paracetamol overdose?
A
occurs in 24 hours after ingestion
pallor, malaise, vomitting, sweating
6
Q
what is the toxic dose of paracetamol?
A
> 10g in 24 hours
or
150mg/kg
7
Q
what is the at risk of toxicity dose?
A
> 7g in 24 hours
or
75mg/kg
