GA1 - liver and gallbladder Flashcards
largest organ in the body
skin
liver and gallbladder are both ___peritoneal
intra-
largest visceral organ in the body
liver
location of the liver
right hypochondrium extending to the left
liver is the chief site of ____ ___
intermediary metabolism
liver secretes ___
bile
bile helps in the digestion of ___; emulsifies ___
fat
fat
liver synthesizes ___ proteins and ___
serum
lipids
serum proteins like ____, ____, ___
albumin, fibrinogen, immunoglobulins
liver processes ____ and ___ substances
endogenous
exogenous
endogenous substances are
drugs you would take will be detoxified as well as alcohol
liver participates in elimination of senescent cells and particulate matter
senescent
senescent cells are ____ cells
aging
von culfer cells - ____ cells
phagocytic
liver in fetal life, it has participated in ___
hematopoiesis
liver has 2 surfaces
diaphragmatic and visceral
diaphragmatic surface has 2 recesses
subphrenic and hepatorenal
livers visceral surface is covered by ___ peritoneum except in the fossa for the ___ and at the ___ ___
visceral
gallbladder
porta hepatis
liver related to the right anterior part of the ____
stomach
liver related to the superior part of ___
duodenum
liver related to the ___ omentum
lesser
liver related to the right ___ ___
colic flexure
liver related to the right ___ colon
transverse
liver related to the right ___ gland and ___
suprarenal
kidney
anterior there looks like there are only ___ lobes
two
structurally caudate and quadrate lobers are part of the ___ lobe but functionally they are part of the ___ lobe
right
left
between caudate and quadrate you will find the fossa/bed for the ____
gallbladder
hilum contains 5 things
R/L hepatic arteries R/L hepatic ducts portal veins sympathetic and parasympathetic nerve fibers lymphatics
2 types of ligaments in the liver
peritoneal and non-peritoneal
4 types of peritoneal ligaments in the liver
falciform
coronary
R/L triangular
lesser omentum
falciform ligament is ____ and separates the ____ and ___ lobes
anteriorly
left and right
falciform ligament is ____ and runs from the ___ to the ____
wide
diaphragm
umbilicus
2 types of non-peritoneal ligaments in the liver
round
ligamentum venosum
round ligament is the reminant of the ____ vein
umbilical
round ligament is the inferior free edge of the ___ ligament
falciform
what makes the caudate and quadrate functionally part of the left lobe?
blood supply and venous drainage is the same
bile for the left lobe, quadrate and caudate will join together to form the __ ___ duct
left hepatic
left and right triangular ligaments attaches to the ____; extensions of ____; extend around to form the ___ ligament
diaphragm
peritoneum
coronary
coronary ligament attaches to the ____
diaphragm
bare area of the liver is not covered by ____ peritoneum; surrounded by the ____ ligament
visceral
coronary
ligamentum teres also called the ____ ligament
round
ligamentum teres contains the obliterated ___ vein
umbilical
ligamentum teres is the inferior edge of the ___ ligament
fulciform
the inferior border is ____; if its rounded, then that means the liver is ____
sharp
enlarged
____ ____ is between the left lobe and caudate
ligamentum venosum
____ ____ ___ between caudate and left lobe
inferior vena cava
ligament of vena cava holds the ___ ___ in place
vena cava
___ ___ between quadrate and left lobe
round ligament/ligamentum teres
common bile duct is the union of left and right ___ ___
hepatic duct
___ is between quadrate and right lobe
gallbladder
left and intermediate hepatic vv. recieve blood from ___ lobe, ___ and ____ and takes deoxygenated blood to the ____ ___ ___
left
caudate
quadrate
inferior vena cava
right hepatic v. takes deoxygenated blood from the ___ lobe to the ___ ____ ___
right
inferior vena cava
portal vein carries deoxygenated blood that is rich in ____ from the ___ and ___ to the liver
nutrients
intestines
stomach
proper hepatic artery carries ____ blood
oxygenated
liver sinusoid are modified ____ that carry blood
capillaries
trace the blood flow from portal v. to IVC
portal v –> portal venules –> sinusoids –> central v. –> sublobular –> hepatic v. –> IVC
celiac trunk is a ___ artery
short
celiac trunk gives off 3 branches (superior, left and right)
superior = left gastric a left = splanchnic a right = common hepatic a
common hepatic artery gives off a superior and inferior branch
superior = proper hepatic artery inferior = gastric duodenal artery
blood supply to the liver
hepatic artery
veins of the liver
portal and hepatic `
portal v is formed by 2 large veins
splenic v
superior mesenteric v
inferior mesenteric v drains into the ___
splenic
inferior mesenteric can sometimes be at the junction of the __ and ___ ___ veins
splenic
superior mesenteric
left gastric v anatomoses with ___ tributaries of the azygous system
esophageal
esophageal varicose v
dilated and enlarged veins
since the blood is being directed somewhere else. 2 things can happen
varicose v or vv can rupture
if the esophageal tributaries rupture it can lead to…
vomiting blood
if the esophageal tributaries become varicose vv…
metallic taste, loss of appetite
paraumbilical vv anastomose with superficial ___ vv
abdominal
paraumbilical vv are along side the ___ ___ ___
ligamentum teres hepatis
paraumbilical vv become snake-like =
capitmedusa
superior rectal vv anastomose with middle and inferior ____ vv
rectal
tributaries of the celiac, superior and inferior mesenteric vv with ___, ___ and ___ vv
renal
phrenic
lumbar
ascites
accumulation of peritoneal fluid in the abdominal cavity
by the superior rectal vv anastomosing with middle and inferior rectal vv it can cause ___ ___
internal hemorroids
liver cirrhosis
liver cells are replaced by fibrous tissue; obstruction of liver sinusoids
when there is an obstruction of the liver sinusoids = portal ____
hypertension
trace the lymphatic drainage of liver from hepatic nodes to the cisterna chyli
hepatic nodes –> celiac nodes –> cisterna chyli
hepatic cephelopathy
uria in the the brain from the liver
hepatic cephelopathy caused by 3 things
alcoholism
hepatitis
liver cancer
nerve supply to the liver
celiac plexus
nerve supply to the liver carries ___ gg parasymp
pre
nerve supply to the liver carries __ gg symp
post
liver has prevertebral gg = ___ gg
celiac
celiac gg around the ___ trunk
celiac
vagus nerve carries ___ and ___ ____ to the liver
GVA; pregg parasymp
sympathetic n are from
lateral horn of T5-T9
sympathetic fibers and vagus carry
GVA
umbilical vv carries ___ blood and become ___ ___ ____
oxygenated
ligamentum teres hepatis
ductus venosus is the connection between ___ v and ____ v
umbilical v
hepatic v
ductus venosus becomes __ __ between the caudate and left lobe
ligamentum venosus
bile is secreted by the ___ and is stored and concentrated in the ___
liver
gallbladder
biliary system contains 4 things
R/L hepatic ducts
common hepatic duct
gallbladder and cystic duct
common bile duct
R/L hepatic duct unite to become
common hepatic duct
common hepatic and cystic unite to become
common bile duct
common bile duct goes to the ___ portion of the duodenum
2nd
main pancreatic duct combines with the ___ ___ ___
common bile duct
gallbladder is a ___-___ sac found on the ___ of the liver
pear-shaped
undersurface
gallbladder has a capacity of __-__ml and stores ___
30-50
bile
3 parts to gallbladder
fundus
body
neck
fundus of the liver is ___ and projects beyond ___ margin of the liver
rounded
inferior
body of the liver lies in contact with ___ surface of liver
visceral
neck of the liver is continuous with the __ duct
cystic
gallbladder concentrates ___
bile
gallbladder releases bile when stimulated by ___
cholecystokinin
blood supply to the gallbladder from ___ artery
cystic
nerve supply to the gallbladder from the ___ plexus
celiac
cystic duct ___in long
1.5
cystic duct is a mucous membrane raised to form a ___ fold
spiral
the spiral fold of the cystic duct keeps the lumen ___
patent
2nd part of the duodenum causing a protrusion =
major duodenal papilla
dilation/opening = hepatopancreatic ampulla which is within the ___ ___ ___
major duodenal papilla
surrounding ampulla is a circular smooth muscle =
hepatopancreatic sphincter
hepatopancreatic sphincter regulates how much __ goes into the ___
bile
duodenum
if the hepatopancreatic sphincter contracts= __ bile from entering and will run ___ to gallbladder
preventing
gallbladder
hepatomegaly
enlargement of the liver which may be due to metastatic carcinoma or liver cirrhosis
jaundice
yellowish discoloration of the skin and sclerae due to hyerbilirubinemia
alcoholic cirrhosis
progressive destruction of hepatocytes and replacement of them by fibrous tissue; usually leads to portal hypertension
cholelithiasis (gallstones)
crystallization of the bile salts and cholesteral
cholelithiasis occurs most in the 5 Fs
female, fat, forties, fertile, flatus gaseous
to correct cholelithiasis - 2 ways
laparoscopic cholecystectomy
ERCP