Four Dopamine Pathways & Schizophrenia Flashcards
1
Q
What are the 4 dopamine pathways?
A
Mesolimbic
Mesocortical
Nigrostriatal
Tuberoypophyseal
2
Q
Which 2 pathways are involved in SZ?
A
Mesolimbic
Mesocortical
3
Q
Function of mesolimbic pathway in SZ?
A
increases DA causing positive symptoms
4
Q
Function of mesocortiyal pathway in SZ?
A
DA hypoactivity causing negative symptoms
5
Q
The drugs used to treat SZ has an effect on which pathways? Causing which symptoms
A
Nigrostriatal
Tuberoypophyseal
6
Q
Nigrostriatal & Tuberoypophyseal cause what symptoms respectively?
A
EPS
hyperprolactinaemia side effects