Foodborne dz in humans and outbreak investigation Flashcards

1
Q

How many deaths a year from contaminated food or water?

A

2 million

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2
Q

How many americans die of foodborne illness a year?

A

3000/year

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3
Q

2 groups of foodborne illness

A

known foodborne pathogens and unknown agents (80% cases)

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4
Q

What are unspecified agents?

A
  • insufficient data to estimate burden
  • knwon agents not yet ID as causing foodborne illness
  • microbes/chemical/other known to be in food but ability to cause illness unproven
  • agents not yet ID
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5
Q

What are the 4 main pathogens causing EU food-borne outbreaks?

A

salmonella
viruses
bacterial toxins
campylobacter

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6
Q

Define outbreak

A

cases clustered in time and space, occurring at higher level than expected

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7
Q

Define epidemic

A

occurrence of ore cases of disease than expected in a given area or among a specific group of people over a particular period of time

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8
Q

What is main food vehicle in EU causing foodborne illness?

A

eggs and egg products

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9
Q

What are the steps during a foodborne outbreak investigation?

A
  • preliminary assessment of situation
  • communication
  • descriptive epidemiology
  • food and environmental investigations
  • analysis and interpretation
  • control measures
  • further studies
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10
Q

3 main objectives in controlling and outbreak

A
  1. reduce to minimum the number of primary cases
  2. reduce to the minimum the number of secondary cases
  3. to prevent further episodes
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11
Q

What is ‘tracing back’?

A

= control of the source of infection or contamination

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12
Q

What is ‘tracing forward’?

A

= taking appropriate action to prevent any subsequent spread

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13
Q

Why draw an epidemic curve?

A

to show the time course of an outbreak

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14
Q

Components of an epidemic curve?

A
  • time of onset of each case
  • set time interval (1/3 or less of incubation period)
  • include time period before and after (2 incubation periods)
  • unknown dz: draw several epidemic curves with different units and select the one that best represents the data
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15
Q

What epidemic pattern is this?

A

point source (1 incubation period)

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16
Q

What epidemic pattern is this?

A

common continuous source (>1 incubation period)

17
Q

What epideic pattern is this?

A

Intermittent common source

18
Q

What epidemic pattern is this?

A

propagated (person to person, an infectious disease)

19
Q

Define ICT

A

Incidence control team

20
Q

Responsibilities

A

protection of public health in relation to food, will assist in investigation of implicated foods

21
Q

Role - local authorities (LA)

A

statutory responsibilty to control outbreaks nd powers of control

22
Q

Role - Primary Care Trust (PCT)

A

can influence primary care resources

23
Q

Role - public health england (PHE)

A

coordinates surveillance

24
Q

Rol e0 local health protection units (HPUs_

A

supports local authorities (LA) in investigation and management of outbreak

25
Q

Role - APHHA

A

assists in outbreak investigation where animal source is implicated

26
Q

3 mehtods of molecular bacterial source tracking

A
  • PCR
  • sequencing
  • restriction enzymes