Flashcard 8 Neuro

1
Q

anti-NMDA autoimmune encephalitis presentation

A
  • flu-like prodrome
  • psychiatric features
  • seizures
  • movement disorders
  • coma
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2
Q

pus in skull management

A
  • IV antibiotics (penicillin, metronidazole)

- drainage if possible

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3
Q

rabies presentation

A
  • N+V
  • foaming at the mouth
  • paraesthesia @ bite site
  • ascending paralysis and encephalitis
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4
Q

most likely cause of extra-dural haemorrhage

A
  • trauma to pterion

skull fractures damage MCA

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5
Q

bacteria causing tetanus

A

clostridium tetani

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6
Q

investigations coma + lateralising and focal brainstem cerebral signs

A
  • CT/ MRI
  • metabolic screens
  • Lumbar puncture (IF no evidence of raised ICP)
  • EEG
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7
Q

how do you differentiate between UMN and LMN facial paralysis

A

LMN - forehead involved

UMN - forehead spared

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8
Q
symptoms:
CONTRALATERAL:
- hemiparesis face/arm/leg
- homonymous hemianopia
- sensory loss
- aphasia
A

MCA stroke - dominant hemisphere

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9
Q

describe cerebral oedema progression

A

brain swelling that may develop within minutes -> coning. normally death

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10
Q

neurosyphilis

A

CNS infection in a patient with syphilis

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11
Q

symptoms:

  • flu-like prodrome
  • progressive headache
  • progressive cerebral impairment
  • confusion
  • abnormal behaviour
  • seizures
  • memory disturbance
A

encephalitis

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12
Q

strict criteria TPA usage

A
  • symptoms >1hr, <4.5hrs
  • disabling neurological deficit
  • consent
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13
Q

communicating hydrocephalus

A

problem with reabsorption of CSF leading to a build uo

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14
Q

myasthenia gravis investigations

A
  • bloods

- nerve conduction studies

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15
Q

glioblastoma multiforme

A
  • astrocytes
  • aggressive
  • spreads by tracking through white matter and CSF pathway
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16
Q

poliomyelitis cause

A
  • polio

- all enteroviruses

17
Q

symptoms:

  • descending symmetrical placid paralysis
  • resp failure
  • autonomic dysfunction
  • pupil dilation
A

botulism

18
Q

what will also be inflamed in posterior uveitis?

A

choroid

19
Q

myopia

A

short sightedness

20
Q

how to manage astigmatism

A

cylindrical glasses which are curved on only 1 axis

21
Q

what causes narcolepsy

A

dysfunctional orexin release from hypothalamus

22
Q

if a person had contralateral homonymous hemianopia making lateral of R eye damaged, what side of brain is damaged

A

left

23
Q

symptoms vit A deficiency

A

night blindness
corneal ulceration
bitots spots

24
Q

ptosis

A

drooping of upper eyelid

25
Q

signs of central retinal artery occlusion

A
  • pupil will not constrict in bad eye (and no indirect effect either)
  • vessels look tatty
  • retina pale and boggy