Flashcard 10
components of process of glycosylation
- accumulation of trapped plasma proteins
2. accumulation of cross-linked basal lamina proteins
potential causes of raised ACR
- UTI
- orthostatic proteinuria
- diabetic kidney disease
how does IGF-1 work
acts as an autocrine to stimulate cartilage production
medications that can cause a rapid rise in [BG]
- steroids
- antipsychotic drugs
what defines a steroid hormone
all derived from cholesterol
4 areas producing steroid hormones
- gonads
- adrenal cortex
- placenta
- kidney
acidotic breathing
Kussmauls
DKA
diabetic ketoacidosis
how do osteoblasts work
highly active laying down extracellular matrix which they can calcify to form boooonnnneeee
thyrotoxicosis
excessive thyroid hormone of any cause
2 hypothalamic inhibiting hormones
dopamine
growth hormone inhibiting
what effect does somatostatin have on insulin and glucagon release
strongly suppresses
hyperthyroidism
excessive production of thyroid hormone by thyroid gland
how do G-protien coupled receptors work?
activates 2nd messenger system -> modification of existing protein
main function vasopressin
anti-diuretic hormone
where do non-trophic hypothalamic neurohormones go when they leave the hypothalamus
hypothalamic nerves -> posterior pituitary-> blood
what 2 peptide neurohormones does the posterior pituitary store and release
vasopressin
oxytocin
autocrine chemical
acts on/ in the same cell that synthesises the hormone
main function oxytocin
milk ejection and uterine contraction
how is an insulinoma indicated
elevated C peptide insulin level
4 general categories for using lab tests?
diagnosis
monitoring
screening
prognosis
