Final Prep/Random Notes Flashcards
What is the output path of the cerebellum?
Purkinje cells (always inhibitory) –> deep cerebellar nuclei –> contralateral cortex via superior cerebellar peduncle
Deep nuclei = Dont Eat Greasy Food
Dentate, Emboliform, Globose, Fastigal
What is Wernicke-Korsakoff Syndrome?
Wernicke problems come in a CAN O’ beer
Confusion
Ataxia
Nystagmus
Ophtalmoplegia
memory loss, confabulation, personality chgs
Due to lesion of mammillary bodies bilaterallly
Where is the lateral horn present in the spinal cord?
T1-L2
Where are the gracile and cuneatus fasciculi both present?
above T7
What do the restiform body + juxtarestiform body make up?
inferior cerebellar peduncle
What normally activates a central pattern generator and what kind of motions does it contorl?
corticla input –> CPG (though to be in spinal cord) –> repetitive actions that can be controlled by same tework of neurons (walking, chewing, etc)
What path does the visual cortex use to relay visual info related to reaching?
dorsal visual path and parietal cortex –> motor cortex
What does TRP-V1 sense?
capsaicin
when on thermoreceptor, if bound –> firing rate increases as temp goes down
What does TRP-M8 sense?
menthol
when on thermoreceptor, if bound –> firing rate increases as temp goes down
What is the receptor btw pre and post ganglionic neurons in both divisions of ANS?
Ach
NAchR
What nerve carries thermosensitive info from the gut?
vagus n
What enzyme produces prostaglandins?
COX
COX1 = present all the time
COX2 = involved in inflammation and fever production
What occurs in heat stroke?
body temp gets so high that the hypothalamus can’t control body temp
How can hypothermia affect chemical reactions?
reduces rate
What are the 3 types of neurons in the paraventricular nucleus?
magnocellular: oxytocin and ADH
Parvocellular: releasing hormones
autonomic controlling –> SNS and PNS
What fibers are in the superior cerebellar peduncle?
afferents from ventral spinocerebellar tract
major efferent route from globose, emboliform, and dentate nuclei
What fibers are in the middle cerebellar peduncle?
afferent from pontine nuclei
What is titubation?
tremor of the trunk in an A-P plane
What vestibular nuclei do you see in the pons?
superior
medial
lateral
What vestibular nuclei do you see in the upper medulla?
medial
lateral
What vestibular nuclei do you see in middle and lower medulla?
medial
lateral
What significant fibers are in the juxtarestiform body of the inferior cerebellar peduncal?
primary vestibulocerebellar efferents
Where does the lateral vestibulospinal tract project?
from lateral and inf vestibular nuclei –> all levels of ipsi SC
anterorostral –> cervical
posterocaudal –> lumbosacral
Where does the medial vestibulospinal tract project?
go do neck muscles bilaterally
input from V receptors, cerebellum, and PCMLS
medial nucleus –> bilaterally thru MLF –> laminae 8 and 9 of cervical SC
What types of fibers are in the brachii of inferior and superior colliculi?
remember SLIM
afferents from auditory sytem go from Inf colliculus –> medial gen body via the brachium
visual input from lateral gen body –> sup colliculus
What does activation of pyramidal cells in the primary motor cortex do?
What layer are these cells located?
output for corticospinal tract –> contract skeletal muscle
layer V
What part of the hypothalamus is responsible for generating autonomic flow?
paraventricular nucleus