FINAL EXAM - Common Medications Flashcards
Adverse drug reactions (ADR) will be seen in
the vital signs
ALWAYS check clients vitals
Parkinson’s L-dopa
when optimal tone effect is reached is the time to treat for therapy
The more medications a person takes, the more….
ADRs a person will experience
Reasons for ADRs(6)
- risk/benefit of drug not recognized
- hx of drug allergy
- wrong drug name or dosage form
- lack of education
- failure to obtain adequate pt. hx and drug hx
- pt compliance issues
Pharmacokinetics (Pk) ADME
- Absorption
- Distribution
- Metabolism
- excretion
Absorption
through stomach and intestinal wall - not fully absorbed
distribution
travels to liver and active in blood stream = travels all around
metabolism
liver first before where it needs to go = partially deactivated
excretion
removed through urine
Pk can be affected by exercise because
the blood goes to the skin and muscles so the drug is not being absorbed by the blood is not going to the GI tract
Side effects are caused by
the drug binding to other areas besides its target organ
Why do we NEVER heat the injection site?
increases absorption
Acidic drugs enter through the
stomach
Transdermal route is
slow - patches for pain, estrogen, nicotine
NEVER put a hot pack over a transdermal patch because
increases absorption and can lead to death!
Intravenous
goes directly to the site - 100% is absorbed
intrathecal
spinal canal - epidural
implanted devices
reservoir implanted- morphine/insulin pump
Common ADR for antimicrobials (3)
- diarrhea
- rash
- pruritus (itching)
Common ADR for Anticoagulants (2)
- hemorrhage
- Bruising
* fine line between enough and too much
Common ADR for Chemotherapy (6)
- bone marrow suppression
- alopecia
- nausea
- infection (decrease in WBC)
- fatigue (decrease in RBC)
- anemia (decrease in RBC)
Common ADR for cardiovascular (3)
- heart block
- arrhythmias
- edema
Common ADR for Diabetic medication (3)
- hypoglycemia (sends people to hospitals)
- diarrhea
- GI complications
Common ADR for NSAIDS (3)
- GI Ulceration and bleeding
- renal insufficiency
- MI
Common ADR for Diuretics (3)
- hypokalemia (low K+)
- hyperglycemia
- dehydration
diabetes and diuretics are not good because
risk of hyperglycemia
body structures and functions commonly affected by ADRs (6)
- hematological system
- skin and related structures
- metabolic
- musculoskeletal
- respiratory
- sensory
Affects to the hematological system (2)
- anemias
2. thrombocytopenia
Affects to the skin and related structures (5)
- pruritus
- urticaria
- alopecia
- rash
- petechiae
Affects to the metabolic system(2)
- osteoporosis
2. fluid and electrolyte imbalance