extrinsic allergic alveolitis Flashcards

1
Q

farmers lung cause

A

aspergillus fumigatas

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2
Q

farmers lung from

A

mouldy hay, straw

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3
Q

malt workers lung

A

aspergillus clavatus

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4
Q

malt workers lung from

A

germinating barley

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5
Q

cheese washers lung

A

aspergillus clavatus and pénicillum casei

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6
Q

cheese washers lung from

A

mouldy cheese

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7
Q

maple bark strippers lung

A

Crytostroma corticaele

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8
Q

pathology

A

infiltration of small airways with neutrophils followed by T lymphocytes and macrophages
leads to non-necrotising granuloma inflammation lungs

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9
Q

what type of granuloma

A

non necrotising

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10
Q

what do the non necrotising granulomas comprise

A

giant cells

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11
Q

what are giant cells

A

multinucleated

formed by the union of several distinct cells - usually macrophages

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12
Q

what type of hypersensitivity reaction

A

III

there is the deposition of immune complexes

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13
Q

what can chronic exposure to antigen cause

A

fibrosis and emphysema

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14
Q

when do the CF arise

A

4-6 hours post exposure

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15
Q

CF

A
fever 
rigors 
myalgia 
dry cough
SOB 
dyspnoea 
crackles
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16
Q

describe the crackles

A

coarse end inspiratory

upper zones

17
Q

chronic CF

A

weight loss
exertional dyspnoea
type 1 resp failure
cor pulmonale

18
Q

treatment

A

steroid and antigen avoidance