extrinsic allergic alveolitis Flashcards
farmers lung cause
aspergillus fumigatas
farmers lung from
mouldy hay, straw
malt workers lung
aspergillus clavatus
malt workers lung from
germinating barley
cheese washers lung
aspergillus clavatus and pénicillum casei
cheese washers lung from
mouldy cheese
maple bark strippers lung
Crytostroma corticaele
pathology
infiltration of small airways with neutrophils followed by T lymphocytes and macrophages
leads to non-necrotising granuloma inflammation lungs
what type of granuloma
non necrotising
what do the non necrotising granulomas comprise
giant cells
what are giant cells
multinucleated
formed by the union of several distinct cells - usually macrophages
what type of hypersensitivity reaction
III
there is the deposition of immune complexes
what can chronic exposure to antigen cause
fibrosis and emphysema
when do the CF arise
4-6 hours post exposure
CF
fever rigors myalgia dry cough SOB dyspnoea crackles