ARDS Flashcards
what is ARDS
acute lung injury, caused by direct injury or secondary to severe systemic illness
most common signs
dyspnoea and hypoxaemia that progress to acute resp failure
what is the pathological finding early in the development
diffuse alveolar damage
outline the pathophysiology
alveolar spaces flooded with inflam cells, oedema fluid and inflam mediators
necrosis and sloughing expose the basement membrane
fibrin deposition creates hyaline membrane
how does the early phase of ARDS manifest
acute hypoxaemic resp failure with inc Aa oxygen gradient and poorly compliant lungs
what may occur if the underlying cause is sepsis
multiple organ failure
outcomes
resolution
lung fibrosis
most common cause
sepsis
what is it a cause of (think fluid)
non cardiogenic pulmonary oedema
what is it often accompanied by
multiple organ failure
CXR
bilateral alveolar shadowing
neonatal RDS
premature babies dont produce enough surfactant
inc effort in expanding lungs causes physical damage to cells
neonatal RDS CXR
ground glass
