Extras: CT and Vasculitides

Question 1

three cardio conditions that SLE is more at risk for

Answer 1

MI, pericarditis, Libman-sacks endocarditis

Question 2

three Abs in APS

Answer 2

1. ACL (anti-cardiolipin)
2. anti-B2 GPI
3. LA (lupus anticoagulant)

Question 3

what condition has a false positive test for syphilis

Answer 3

APS

Question 4

how is DIL different from SLE

Answer 4

no neuro or renal sx

Question 5

Abs in DIL

Answer 5

anti-histone Abs

Question 6

major issue in neonatal lupus

Answer 6

congenital heart block

Question 7

two tx for pregnant pt with anti-Ro Abs to avoid neonatal lupus

Answer 7

1. dexamethasone while pregnant

2. hydroxychloroquine to prevent in next pregnancy

Question 8

best treatment for all systemic scerlosis / scleroderma

Answer 8

symptomatic only - no current significant therapies

Question 9

what type of SSc is associated with ILD vs PAH

Answer 9

ILD: diffuse
PAH: limited/CREST

Question 10

skin patches in localized scleroderma

Answer 10

morphea

Question 11

abs in limited vs diffuse scleroderma

Answer 11

1. limited: anti-centromere Abs

2. diffuse: anti-topoisomerase (Scl70), anti RNA Pol III

Question 12

Abs in dermatomyositis and polymyositis

Answer 12

anti-Jo1

Question 13

what two labs are increased in inflammatory myopathies

Answer 13

CK, aldolase

Question 14

inclusion body myositis

Answer 14

weakness in: finger flexion / quads

Question 15

tx for dermatomyositis and polymyositis

Answer 15

glucocorticoids

Question 16

tetrad of IgA vasculitis

Answer 16

1. purpura
2. arthralgias
3. abdominal pain
4. glomerulonephritis

Question 17

other name for Goodpasture syndrome

Answer 17

anti-glomerular basement membrane syndrome

Question 18

ANCA in granulomatosis with Polyangiitis vs eosinophilic granulomatosis with polyangiitis

Answer 18

1. GPA: c-ANCA

2. Eosinophilic GPA: p-ANCA

Question 19

what vasculitide has crescentic glomerulonephritis

Answer 19

eosinophilic granulomatosis with polyangiitis (Churg-Strauss)

Question 20

Ab in microscopic polyangiitis

Answer 20

pANCA

Question 21

HLA associated with Bechet?

Answer 21

HLA-B51

Question 22

how to dx secondary raynaud’s (primary theres no dx method)

Answer 22

nailfold capillaroscopy -> irreg loops with dilated lumens, vascular dropout

Question 23

what vasculitide classically spares the lungs?

Answer 23

PAN

Question 24

treatment for Kawasaki disease

Answer 24

ASA + IVIG within 10 days of dx

Question 25

what vasculitide is considered a “pulseless disease”

Answer 25

Takayatsu arteritis