Extras: CT and Vasculitides Flashcards
three cardio conditions that SLE is more at risk for
MI, pericarditis, Libman-sacks endocarditis
three Abs in APS
- ACL (anti-cardiolipin)
- anti-B2 GPI
- LA (lupus anticoagulant)
what condition has a false positive test for syphilis
APS
how is DIL different from SLE
no neuro or renal sx
Abs in DIL
anti-histone Abs
major issue in neonatal lupus
congenital heart block
two tx for pregnant pt with anti-Ro Abs to avoid neonatal lupus
- dexamethasone while pregnant
2. hydroxychloroquine to prevent in next pregnancy
best treatment for all systemic scerlosis / scleroderma
symptomatic only - no current significant therapies
what type of SSc is associated with ILD vs PAH
ILD: diffuse
PAH: limited/CREST
skin patches in localized scleroderma
morphea
abs in limited vs diffuse scleroderma
- limited: anti-centromere Abs
2. diffuse: anti-topoisomerase (Scl70), anti RNA Pol III
Abs in dermatomyositis and polymyositis
anti-Jo1
what two labs are increased in inflammatory myopathies
CK, aldolase
inclusion body myositis
weakness in: finger flexion / quads
tx for dermatomyositis and polymyositis
glucocorticoids
tetrad of IgA vasculitis
- purpura
- arthralgias
- abdominal pain
- glomerulonephritis
other name for Goodpasture syndrome
anti-glomerular basement membrane syndrome
ANCA in granulomatosis with Polyangiitis vs eosinophilic granulomatosis with polyangiitis
- GPA: c-ANCA
2. Eosinophilic GPA: p-ANCA
what vasculitide has crescentic glomerulonephritis
eosinophilic granulomatosis with polyangiitis (Churg-Strauss)
Ab in microscopic polyangiitis
pANCA
HLA associated with Bechet?
HLA-B51
how to dx secondary raynaud’s (primary theres no dx method)
nailfold capillaroscopy -> irreg loops with dilated lumens, vascular dropout
what vasculitide classically spares the lungs?
PAN
treatment for Kawasaki disease
ASA + IVIG within 10 days of dx
what vasculitide is considered a “pulseless disease”
Takayatsu arteritis
