4: CT Diseases Flashcards

1
Q

other name for cANCA and pANCA

A
cANCA = PR3-ANCA
pANCA = MPO-ANCA
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2
Q

pericarditis presentation

A

substernal constant CP thats worse with cough, deep inspiration, supine; better with sitting up/leaning forward

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3
Q

pericarditis on ECG

A

diffuse ST elevation

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4
Q

why are SLE pts at higher risk of MI?

A

accelerated atherosclerosis

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5
Q

mortality in SLE during early vs later years

A

early: infections w opportunistic infection, kidney or CNS disease
late: accelerated atherosclerosis, MI, thromboembolic events

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6
Q

explain lupus anticoagulant (LA): in vivo vs in vitro

A

In vivo: procoagulant

in vitro: anti-coagulant - prolongs PTT

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7
Q

examples of some meds that can cause DIL - drug-induced lupus

A

procainamide, hydralazine, isoniazid, methyldopa, lithium, phenytoin, nitrofurantoin, sulfasalazine, HCTZ, simvastatin

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8
Q

DDx of discoid lupus (what it looks like)

A

tinea (ringworm), psoriasis, morphea (localized scleroderma)

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9
Q

first symptoms of Scleroderma in white vs black pts

A

white: raynaud’s
black: pigmentation changes

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10
Q

primary cause of morbidity and mortality in systemic sclerosis

A

pulmonary sx

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11
Q

ILD: interstitial lung disease presentation

A

chronic dry cough, dyspnea, “velcro” like crackles/rales

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12
Q

how to Dx interstitial lung disease

A

PFT

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13
Q

PAH: pulmonary artery HTN presentation

A

exertional dyspnea, syncope, angina, R heart failure, increased bronchoalveolar carcinoma

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14
Q

how to Dx PAH (pulmonary artery hypertension)

A

right heart cath

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15
Q

renal crisis presentation**

A

abrupt onset: malignant HTN, hemolytic anemia, progressive renal insufficiency

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16
Q

what treatment can induce renal crisis in pts with systemic sclerosis?***

A

high dose glucocorticoids

17
Q

when would you bx a parotid gland in sjogren’s?

A

pts with atypical presentation to r/o cancer

18
Q

treatment for sjogrens

A

treat sicca symptoms symptomatically, glucocorticoids for extraglandular manifestations

19
Q

Gottron’s papules

A

raised violaceous lesions on dorsa of DIP, PIP, and MCP

20
Q

heliotrope rash

A

periorbital edema, purple red discoloration