exam review Flashcards
what are formed elements? Which formed elements have nuclei?
Erythrocytes, leukocytes and platelets.
Leukocytes have a nucleus; erythrocytes lose their nucleus during the last stage of erythropoiesis.
What is the lifespan of an erythrocytes and why?
The average lifespan is 120 days because they do not have a nucleus and therefore cannot duplicate.
What is the term for decreased number of platelets?
thrombocytopenia
what are important plasma proteins and what are their functions?
Albumin- osmotic pressure
Globulin- antibodies
Fibrogen- Forms fibrigin
What triggers erythropoiesis?
Lack of oxygen, increased tissue demand
What organ is responsible for producing erythropoietin?
kidney
Where are RBC’s produced?
Red bone marrow
which blood clotting disease is transmitted by the x chromosome?
Hemophilia
more common in men than women
What is iron-deficiency anemia?
What is anemia?
RBC unable to carry oxygen adequately
what is pernicious anemia?
Autoimmune disease where body prevents you from absorbing B12
what is renal anemia?
Kidneys can not produce enough EPO so RBC count drops
what is aplastic anemia and sickle cell?
In what ways is blood an atypical type of connective tissue?
is a liquid tissue but has the same
elements as other types of connective tissue; solid fibers only appear during clotting
What are the steps of coagulation?
vascular spasm, blood vessel constricts to prevent further blood loss, platelet plug (platelets stick to damaged area of torn vessel to help seal break) coagulation- reinforces the platelet plug by later producing fibrin threads.
where are antigens and antibodies found?
Antigens are found on the RBC membranes, they
trigger a response from the recipient’s immune system. Antibodies are found in the plasma.
What blood type can receive blood from any donor?
AB+ because since all antigens are
present on their RBC there are no antibodies in the plasma
Which blood type is the universal donor and why?
O- blood because the RBC has no antigens
What is erythroblastosis fetalis and when does it occur?
Occurs during a second pregnancy
when the mother is Rh- and the baby is Rh+. In this case, the Rh+ antibodies from the mother
will cross the placenta and destroy the baby’s RBCs.
What are the anatomical landmarks for the heart?
The heart lies in the mediastinum, sits on
the surface of the diaphragm, left ventricle forms the apex and points toward the left hip
Know the gross anatomy of the heart. For example, where is the coronary sulcus located?
Between atria and ventricles
What happens if there is any blockage of a coronary artery
Ischemia (lack of oxygen) to the
cardiac muscle that is served by that specific coronary artery
What are the branches of the left coronary artery?
Anterior interventricular branch and
circumflex branch
What are the branches of the right coronary artery?
Posterior
interventricular artery and left marginal artery
Know the chambers, valves and be able to trace blood as it travels through the heart. What
part of the cardiac cycle would be affected if there is narrowing (stenosis) of the pulmonary
valve?
It would affect blood leaving the right ventricle that goes into the pulmonary trunk
Know the phases of cardiac cycle and the main events that happen in each. What occurs during
atrial contraction?
Ventricular filling and gravity plays a role
What happens during
ventricular contraction?
Blood is ejected from the ventricles and goes into the great vessels
(aorta and pulmonary trunk
What happen during isovolumetric contraction, ventricular
relaxation and isovolumetric relaxation?
In both cases the volume remains the same (because
all valves are closed) and only ventricular pressure changes
What valves are closed at the beginning of ventricular systole?
AV valves because during
ventricular contraction, blood is ejected into the aorta and pulmonary trunk.