EXAM 4/10 Flashcards
Be able to name the endocrine glands and identify where they’re located in the body
Pineal gland, hypothalamus, pituitary gland, thyroid gland, parathyroid glands, thymus, adrenal glands, pancreas and gonads
What are hormones?
Chemical messengers (usually long distance chemical signals that travel through blood or lymph) that bind to the receptors on target cells
Target cells have receptors that only respond to specific hormones.
What are autocrines
Short distance chemical signals that exert their effects on the same cells that secrete them.
What are the types of stimuli that trigger endocrine glands to manufacture and release their hormones
Humoral, neural and hormonal mechanism
How does the hypothalamus interact with the anterior pituitary? And what are the hormones released from the anterior pituitary
They interact through a blood connection and releasing+ inhibiting hormones are released. The anterior pituitary releases growth hormone (GH), thyroid stimulating hormone (TSH), adrenocorticotropic hormone (ACTH), follicle stimulating hormone (FSH), luteinizing hormone (LH) and prolactin (PRL)
How does the hypothalamus interact with the posterior pituitary? What hormones are released from the posterior pituitary gland?
There is a nerve connection between the hypothalamus and posterior pituitary gland. Hypothalamus neurons synthesize hormones and they are released from the posterior pituitary gland. Oxytocin and antidiuretic released.
What is the function of oxytocin and where is the target receptor for this hormone?
Oxytocin is responsible for causing contractions and milk ejection from the breast
What homeostatic imbalance occurs when there is a decrease in ADH? (Antidiuretic). - helps blood vessels constrict and helps the kidneys control the amount of blood and salt in the body.
Diabetes insipidus. When a patient is dehydrated BP may drop, large amounts of urine.
What homeostatic imbalance occurs when there is a decrease in GH?
Pituitary dwarfism in children.
What homeostatic imbalance occurs when there is an increase in GH?
Gigantism in children and acromegaly in adults
What homeostatic imbalance occurs when there is an increase in TSH? Thyroid stimulating hormone
Hyperthyroidism
Exophthalmos (bulging eyes) seen in patients with hypersecretion of thyroxine.
-Can cause graves disease when antibodies mimic TSH. Overproduction of hormones from the thyroid
What homeostatic imbalance occurs when there is a decrease in TSH?
Hypothyroidism, may cause myxedema (swelling of ankles and feet are symptoms of this)
Iodine is the central ion in both thyroid hormones. What can result from a deficiency in iodine? How are the thyroid hormones produced? (Thyroxine T4 and triiodothyronine T3)
Formation of a thyroid goiter. (Enlarged thyroid)
Produced in the colloid and then taken into the follicular cell by endocytosis
What homeostatic imbalance occurs when there is an increase in ACTH? (Adrenocorticotropic hormone) produced by the anterior pituitary. What are the symptoms of this disease or syndrome?
Cushing’s disease (buffalo hump and fat deposition midback and belly) ,some more symptoms include increased glucose levels and tissue swelling
What is the function of FSH in females? (Follicle stimulating hormone) hormone released by the pituitary gland in the brain
Helps control the menstrual cycle and helps mature developing ovary eggs - oocyte
What is the function of FSH in males? ( Follicle stimulating hormone) hormone releases by the pituitary gland in the brain
Helps mature sperm
What is the function of LH in females? (Luteinizing hormone)
Triggers ovulation in females
What is the function of LH in males?
(Luteinizing hormone)
Causes the testicles to produce testosterone which is important to
sperm production, so a male with low LH will have low sperm count
FSH and LH are referred to as gonadotropins because they stimulate the gonads
True
What is the function of PRL (prolactin)
Causes the breasts to grow and Increases milk production during pregnancy and after birth
What is the function of calcitonin and parathyroid hormone
Both of these hormones regulate calcium metabolism. Calcitonin is produced by the parafollicular cells (c cells) of the thyroid gland. Calcitonin can have a bone sparing effect at higher doses therefore inhibiting osteoclast activity to inhibit bone resorption and stimulate calcium uptake from the blood into the bony matrix.
Calcitonin opposes the actions of the parathyroid hormone which is to increase your blood calcium levels so calcitonin decreases it.
What are the layers of the adrenal cortex and what hormones are produced from each layer
The outermost is the zona glomerulosa which produces aldosterone(regulates salt and water in body) (a mineralocorticoid). The middle layer is the zona fasciculata which produces cortisol(a glucocorticoids)(primary stress hormone) the innermost layer is the zona fasciculata which produces androgens (contributes to growth in both men and women)
What happens if there is a tumor in the zona fasciculata that causes hypersecretion of hormones produced in that region? What is the function of these hormones?
There is an increase in cortisol (glucocorticoids)
Glucocorticoids enable the body to deal appropriately with stress. They do this by increasing blood glucose levels and blood pressure