Endocrine Flashcards
Endocrinology
Study of hormones and endocrine organs
Endocrine glands
Produce hormones
Lack ducts
Examples: pituitary, thyroid, parathyroid, adrenal and pineal glands
Neuroendocrine organ
Hypothalamus
Exocrine and endocrine functions
Pancreas, gonads, placenta
Hormones
Long-distance chemical signals;travel in blood or lymph
Autocrines
Chemicals that exert effects on the same cells that secrete them
Paracrines
Locally acting chemicals that affect cells other than those that secrete them
Two main classes of hormones
Amino acid-based hormones
and steroids
Eicosandoids
Possible third class of hormone
Target cells
Tissues with receptors for a specific hormone
Water soluble hormones
(all amino acid-based hormones except thyroid hormone)
Act on plasma membrane receptors
Act via G protein second messengers
Cannot enter cell
Lipid soluble hormones
(steroid and thyroid hormones)
Act on intracellular receptors that directly activate genes
Can enter cell
Blood levels of hormones are controlled by
Negative feedback systems.
-increased hormone effects on target organs can inhibit further hormone release
Hormone release is triggered by
Endocrine gland stimuli and
nervous system modulation
Hormonal stimuli
Hormone release caused by altered levels of certain critical ions or nutrients