Exam 3: Chapter 37: Assessment and Management of Patietns with Allergic Disorders Flashcards
What is a Allergy?
Inappropriate often harmful response in the immune system to a usually harmless item
What is a Allergen?
Substance that causes manifestations of allergy. The substance that causes the allergy response
What is a Atopy?
Genetic component of what we are allergic to. This includes peanuts, nuts, mushrooms. The chemical mediator is released due to this exposure
What is an Allergic Reaction?
Manifestation of tissue injury due to interaction between antigen and antibody. This causes the inflammatory response. Body defenses recognize these as foreign and the body attempts to remove these objects from the body
What lymphocytes respond to the antigen, what is produced?
Antibodies
What is the key and what is the lock in the specificity example?
ANtigens are the keys, and they fit only certain antibodies
Immunoglobulins can be found where?
In the lymph nodes, tonsils, appendix, and Peyer patches of the intestinal tract or circulating in the blood and lymph
Antibodies that are formed by lymphocytes and plasma cells are known as what?
Immunoglobulins
IgE antibodies are involved with
allergic disorders.
If performed a blood test after allergic reaction, what should be present?
Eosinophils and Basophils
IgE producing cells are located in the
respiratory and intestinal mucosa
Two or more IgE molecules bind together to an allergic and trigger
mast cells or basophils to release chemical mediators, such as histamine. This produces a allergic skin reaction, astha, and hay fever
When IgE molecules bind, what chemical mediators do they release?
Histamine, Serotonin, Kinins, SRS-A (Slow Reactions Substances of Anaphylaxis) and Neutrophil Factor
Histamine released in a allergic reaction produces what type fo response?
Eyes/Nose Watering and the individual sneezing
B Cells are programmed to
produce one specific antibody.
When encountering a specific antigen
B Cells stimulate production of plasma cells
T Cells assist the
B cells
T Cells secrete
substances that direct te flow of cell activity, destroy target cells, and stimulate the macrophages. Macrophages present the antigens to the T Cell
Example of Complete Protein Antigens?
Animal dander, pollen, and horse serum, stimulate a complete humoral response
What plays a major role in IgE-mediated immediate hypersensitivity?
Mast cells. Allergen triggers B Cell to make IgE antibody. When allergen reappears, it binds to the IgE and triggers the mast cell to release its chemicals
In Allergic Response, where are Histamine 1 and 2 Located?
1 located in Bronchail and 2 located in the gastric area
Two types of chemical mediators?
Primary and SEcondary
Primary MEdiators are
preformed and found in mast cells of basophils
Secondary Mediators
inactive precursors that are formed or released in response to primary mediators