Exam 1: Sodium Imbalances Flashcards

1
Q

Most abundant electrolyte in ECF?

A

Na

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2
Q

Concentration of Na?

A

135-145

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3
Q

Primary role of Sodium?

A

Controlling water distribution throughout body, because it doesd not easily cross the cell wall membrane.

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4
Q

What is Sodium regulated by?

A

ADH, Thirst, and RAAS

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5
Q

Loss or gain or sodium is usually accompanied by?

A

Loss or gain of water

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6
Q

SIADH may be associated with?

A

Sodium imbalance

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7
Q

When is Arginine Vasopressin (AVP) released?

A

When there is a decrease in the circulating plasma osmolality, blood volume, or blood pressure

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8
Q

What can oversecrection of AVP cause?

A

SIADH

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9
Q

Sodium Deficit name?

A

Hyponatremia

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10
Q

Sodium Excess Name?

A

Hypernatremia

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11
Q

Hyponatremia Contributing Factors?

A

Loss of Sodium through diuretics, renal disease, gain of wwater, and disease states associated with SIADH

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12
Q

Hyponatremia Signs/Symptoms

A

Anorexia, Nausea and Vomiting, Headache, Decreased BP/Pulse, Dry Skin, Weight Gain, Edema

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13
Q

Hyponatremia Labs Indicate

A

Decreased Serum and Urine Sodium

Decreased Urine Specific Gravity and Osmolality

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14
Q

Hypernatremia Contributing Factors

A

Fluid deprivation in patients who don’t respond to thirst.
Diabetes Insipidus
Watery Diarrhea

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15
Q

Hypernatremia Signs/Symptoms

A

Thirst, Elevated Body Temperature, Seizures, Increased BP and Pulse

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16
Q

Hypernatremia Labs Indicate

A

Increased Serum Sodium
Decreased Urine Sodium
Increased Urine Specific Gravity and Osmolality
Decreased Central Venous Pressure

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17
Q

Hyponatremia refers to serum sodium level that is

A

less than 135 mEq / L

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18
Q

Acute Hyponatremia is commonly the result of

A

a fluid overload in a surgical patient

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19
Q

Chronic hyponatremia is more frequently

A

in patients outside a hospital setting, has longer duration

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20
Q

Low Urine Sodium occurs as

A

the kidneys retains sodium to compensate for nonrenal fluid loss (vomiting, diarrhea, sweating)

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21
Q

High Urine Sodium concentration is associated with

A

renal salt washing

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22
Q

What medications increase the risk of hyponatremia?

A

Anticonvulsants, Oxcarbazepine, Levetiracetam, SSRIs, SErtraline, Paroxetine, or Desmopressin Acetate

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23
Q

Neurologic changes of hyponatremia?

A

Altered mental status, status epilepticus and coma

24
Q

Hyponatremia: What happens as extracellular sodium level decreases?

A

The cellular fluid becomes relatively more concentrated and pulls water into the cells.

25
Acute decreases in sodium may be associated with?
Brain herniation, and compression of midbrain strcutres
26
What signs can ocur when Serum Sodium levels decreases to less than 115 mEq/L?
Signs of increasing intracranial pressure, such as lethargy, confusion, muscle twitching, focal weakness, hemiparesis, seizures, or death
27
Sodium level in hyponatremia?
Less than 135 mEq/L
28
Sodium level in SIADH?
May be lower than 100 mEq/L
29
When hyponatremia is due primarily to sodium loss, the urinary sodium content is
less than 20 mEq/L, suggesting proximal reabsorption of sodium secondary to ECF volume depletion
30
Hyponatremia SpG?
1.002 to 1.004
31
Urinary Sodium Content and SpG when Hyponatremia due to SIADH?
Greater than 20 mEq.L and urine specific gravity is usually greater than 1.012
32
Most common treatment for hyponatremia is?
Careful administration of sodium by mouth, nasogastric tube, or parenteral route
33
Sodium replacement for patients who can eat and drink?
Sodium easily replaced because it is consumed abundantly in a normal diet
34
Sodium replacement for those who cnanot consume sodium?
Lactated Ringer solution or isotonic saline (0.9% sodium chloride)
35
usual daily sodium requirement in adults?
Approximately 100 mEq
36
In patients with normal or excess fluid volume, hyponatremia is usually treated effectively by
restricting fluid
37
Hyponatremia: Pharmacologic Therapy treatments?
AVP Receptor Antagonists Vaprisol Tolvaptan
38
What do AVP Recceptor Antagonists do?
Pharmacologic agents that treat hyponatremia by stimulating free water excretion
39
What does Vaprisol do?
Limited to hospitalized patients. May be useful therapy for those patients with moderate to severe symptomatic hyponatremia, but not those with seizures or in a coma
40
What does Samsca do?
Oral medication for clinically significant hypervolemic and euvolemic hyponatremia
41
Hyponatremia is a frequently overlooked cause of what?
Confusion in older patients who are at increased risk because of decreased renal function
42
What should a nurse monitor?
I/O, Weight, and be alert for GI Manifestations
43
Hypernatremia is
a serum sodium level higher than 145 mEq/L
44
How is Hypernatremia caused?
By a gain of sodium in excess of water or by a loss of water in excess of sodium
45
Hypernatremia can occur in patients with
normal fluid volume, or those with FVD or FVE
46
Hypernatremia, what happens in water loss?
Patient loses more water than sodium, as a result, the sodium concentration icnreases and the increased concentration pulls fluid out of the cell
47
Common cause of hypernatremia?
Fluid deprivation in patients who cannot respond to thirst.
48
Less common causes of hypernatremia??
Heat Stroke, NEar Drowning in Sea Water, and Malfunction of hemodialysis or peritoneal dialysis systems
49
Clinical manifestations of hypernatremia?
Are owing to increased plasma osmolality causedby an increase in plasma sodium concentration. Water moves out of the cell into the ECF
50
Serum Sodium levels in hypernatremia?
> 145 mEq/L
51
Serum Osmolality in Hypernatremia?
300 mOsm / kg
52
Urine SpG and Urine Osmolality in hypernatremia?
Increased as kidneys attempt to converse water.
53
Treatment of hypernatremia consists of
gradual lowering of the seurm sodium level by the infusion of a hypotonic electrolyte solution (0,3% sodium chloride) or an isotonic nonsaline solution (dextrose 5% in water).
54
Why is Hypotonic thought to be safer than Isotonic?
Allows gradual reduction in the serum sodium level, thereby decreasing the risk of cerebral edema
55
How should a nurse prevent hypernatremia?
By providing oral fluids at regular intervals
56
How should a nurse prevent hypernatremia if patient unconscious?
By enteral feedings or by the parenteral route.