Exam 1 Quizlet questions

Question 1

Who discovered that silkworm disease can be caused by a fungus?

Answer 1

Bassi

Question 2

Who developed a vaccine for smallpox?

Answer 2

jenner

Question 3

What part of our immune defenses is involved in making antibodies?

Answer 3

humoral

Question 4

What cells of the innate immune response eliminate virally infected host cells?

Answer 4

Natural Killer Cells

Question 5

Which of these is true of our innate immunity?

Answer 5

it is non-specific

Question 6

Which of these is NOT true of the innate immune system?

Answer 6

It takes 7 to 10 days to begin a response

Question 7

Which of these cytokines is secreted in response to viral infection?

Answer 7

Interferon

Question 8

IL-1 is activated by the action of what protein?

Answer 8

Capase 1

Question 9

What type of action do most cytokines produce?

Answer 9

Paracrine

Question 10

During the oxidative burst, what reactive oxygen species is produced by NADPH oxidase?

Answer 10

Superoxide

Question 11

Which of these is the most important transciption factor for responding to LPS?

Answer 11

NFkB

Question 12

Which of these is the C3 convertase of the alternative cascade?

Answer 12

C3bBbP

Question 13

Which of these is the C5 convertase of the classical cascade?

Answer 13

C2b4b3b

Question 14

Which complement cascade involves the action of MASPs?

Answer 14

Alternative

Question 15

What is the main anaphylatoxin produced in the complement cascade?

Answer 15

C5a

Question 16

What is the main opsin in the complement cascade?

Answer 16

C3b

Question 17

Which of these is NOT a common function of antibodies?

Answer 17

direct killing of pathogens

Question 18

Which of these is involved in antigen presentation of extracellular pathogens?

Answer 18

MHC II and CD-4 T-cells

Question 19

Which of these is involved in antigen presentation of intracellular pathogens?

Answer 19

MHC I and CD-8 T-cells

Question 20

What protein acts as the signalling domain for the B-cell receptor?

Answer 20

Ig alpha and beta

Question 21

What protein acts as the signaling domain for the T-cell receptor?

Answer 21

CD-3

Question 22

Elimination of self-reactive T-cell during development is an important part of ____.

Answer 22

central tolerance

Question 23

Which of the following people created the first vaccines for anthrax and rabies?

a. Metchnikoff
b. Fleming
c. Jenner
d. Pasteur

Answer 23

Pasteur

Question 24

What is the only human disease to be eradicated by immunization?

a. Rabies
b. Polio
c. Smallpox
d. Measels

Answer 24

smallpox

Question 25

With what part of the immune system are Peyer's patches associated? a. Spleen b. Thymus c. Lymph nodes d. GALT

Answer 25

GALT

Question 26

Which of the following us true of the COX1 enzyme, but not COX2? a. It is involved in blood clotting b. It is inhibited by steroids c. It is inhibited by aspirin d. It is induced during infections

Answer 26

it is involved in blood clotting

Question 27

Which is true of the secondary immune response? a. Mostly IgM is produced b. Antibodies of low affinity are produced c. Prior exposure to the antigen is required d. It produces no lasting immunological memory

Answer 27

prior exposure to the antigen is required

Question 28

What is the most numerous white blood cell in the peripheral circulation? a. Erythrocyte b. Eosinophil c. Neutrophil d. Lymphocyte

Answer 28

neutrophil

Question 29

Which of the following cells is part of the innate immune defense? a. Plasma cell b. Macrophage c. Memory cell d. T-cell

Answer 29

macrophage

Question 30

Which of these proteins is created through genetic rearrangements of gene segments? a. Fc Receptor b. Chemokine receptor c. Il-1 receptor d. T-cell receptor

Answer 30

T-cell receptor

Question 31

Which of these is NOT an important antigen presenting cell? a. T-cell b. Neutrophil c. Macrophage d. Dendritic cell

Answer 31

T-cell

Question 32

Which of these proteins does NOT contain multiple immunoglobulin folding domains? a. Antibody b. T-cell Receptor c. Chemokine receptor d. MHC class II molecule

Answer 32

Chemokine receptor

Question 33

What process is involved in expanding populations of useful lymphocytes during the immune response to a pathogen? a. Clonal deletion b. Clonal selection c. Isotype switching d. Apoptosis

Answer 33

clonal selection

Question 34

What organ is most responsible for clearing old blood cells and antigen-antibody complexes? a. Thymus b. Bone marrow c. Kidneys d. Spleen

Answer 34

spleen

Question 35

What sort of ligands are recognized by TLR, CLR, NLR and RLR? a. Cytokines b. Chemokines c. Pathogen-associated patterns d. Antigens on presenting cells

Answer 35

pathogen associated patterns

Question 36

Which of the following is a quality of an excellent antigen? a. Small size b. Similarity to host tissues c. Chemical complexity d. Presentation on foreign MHC molecule

Answer 36

chemical complexity

Question 37

What is the most potent chemoattractant produced in the complement system? a. C1qrs b. C6 c. C3b d. C5a

Answer 37

C5a

Question 38

Neutrophils are formed in the ________________precursor cell line.

Answer 38

Myeloid

Question 39

IgA, IgG, and IgD are different ___________ of antibodies.

Answer 39

Isotypes

Question 40

A protein found on our skin called _____________kills Escherichia coli on contact.

Answer 40

Psoriasin

Question 41

The complement cascade can kill pathogens by forming a pore called ________________.

Answer 41

MAC