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Immunology Quiz Questions > Exam 1 Quizlet questions > Flashcards

Exam 1 Quizlet questions Flashcards

1
Q

Who discovered that silkworm disease can be caused by a fungus?

A

Bassi

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2
Q

Who developed a vaccine for smallpox?

A

jenner

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3
Q

What part of our immune defenses is involved in making antibodies?

A

humoral

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4
Q

What cells of the innate immune response eliminate virally infected host cells?

A

Natural Killer Cells

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5
Q

Which of these is true of our innate immunity?

A

it is non-specific

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6
Q

Which of these is NOT true of the innate immune system?

A

It takes 7 to 10 days to begin a response

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7
Q

Which of these cytokines is secreted in response to viral infection?

A

Interferon

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8
Q

IL-1 is activated by the action of what protein?

A

Capase 1

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9
Q

What type of action do most cytokines produce?

A

Paracrine

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10
Q

During the oxidative burst, what reactive oxygen species is produced by NADPH oxidase?

A

Superoxide

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11
Q

Which of these is the most important transciption factor for responding to LPS?

A

NFkB

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12
Q

Which of these is the C3 convertase of the alternative cascade?

A

C3bBbP

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13
Q

Which of these is the C5 convertase of the classical cascade?

A

C2b4b3b

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14
Q

Which complement cascade involves the action of MASPs?

A

Alternative

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15
Q

What is the main anaphylatoxin produced in the complement cascade?

A

C5a

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16
Q

What is the main opsin in the complement cascade?

A

C3b

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17
Q

Which of these is NOT a common function of antibodies?

A

direct killing of pathogens

18
Q

Which of these is involved in antigen presentation of extracellular pathogens?

A

MHC II and CD-4 T-cells

19
Q

Which of these is involved in antigen presentation of intracellular pathogens?

A

MHC I and CD-8 T-cells

20
Q

What protein acts as the signalling domain for the B-cell receptor?

A

Ig alpha and beta

21
Q

What protein acts as the signaling domain for the T-cell receptor?

A

CD-3

22
Q

Elimination of self-reactive T-cell during development is an important part of ____.

A

central tolerance

23
Q

Which of the following people created the first vaccines for anthrax and rabies?

a. Metchnikoff
b. Fleming
c. Jenner
d. Pasteur

A

Pasteur

24
Q

What is the only human disease to be eradicated by immunization?

a. Rabies
b. Polio
c. Smallpox
d. Measels

A

smallpox

25
Q

With what part of the immune system are Peyer’s patches associated?

a. Spleen
b. Thymus
c. Lymph nodes
d. GALT

A

GALT

26
Q

Which of the following us true of the COX1 enzyme, but not COX2?

a. It is involved in blood clotting
b. It is inhibited by steroids
c. It is inhibited by aspirin
d. It is induced during infections

A

it is involved in blood clotting

27
Q

Which is true of the secondary immune response?

a. Mostly IgM is produced
b. Antibodies of low affinity are produced
c. Prior exposure to the antigen is required
d. It produces no lasting immunological memory

A

prior exposure to the antigen is required

28
Q

What is the most numerous white blood cell in the peripheral circulation?

a. Erythrocyte
b. Eosinophil
c. Neutrophil
d. Lymphocyte

A

neutrophil

29
Q

Which of the following cells is part of the innate immune defense?

a. Plasma cell
b. Macrophage
c. Memory cell
d. T-cell

A

macrophage

30
Q

Which of these proteins is created through genetic rearrangements of gene segments?

a. Fc Receptor
b. Chemokine receptor
c. Il-1 receptor
d. T-cell receptor

A

T-cell receptor

31
Q

Which of these is NOT an important antigen presenting cell?

a. T-cell
b. Neutrophil
c. Macrophage
d. Dendritic cell

A

T-cell

32
Q

Which of these proteins does NOT contain multiple immunoglobulin folding domains?

a. Antibody
b. T-cell Receptor
c. Chemokine receptor
d. MHC class II molecule

A

Chemokine receptor

33
Q

What process is involved in expanding populations of useful lymphocytes during the immune response to a pathogen?

a. Clonal deletion
b. Clonal selection
c. Isotype switching
d. Apoptosis

A

clonal selection

34
Q

What organ is most responsible for clearing old blood cells and antigen-antibody complexes?

a. Thymus
b. Bone marrow
c. Kidneys
d. Spleen

A

spleen

35
Q

What sort of ligands are recognized by TLR, CLR, NLR and RLR?

a. Cytokines
b. Chemokines
c. Pathogen-associated patterns
d. Antigens on presenting cells

A

pathogen associated patterns

36
Q

Which of the following is a quality of an excellent antigen?

a. Small size
b. Similarity to host tissues
c. Chemical complexity
d. Presentation on foreign MHC molecule

A

chemical complexity

37
Q

What is the most potent chemoattractant produced in the complement system?

a. C1qrs
b. C6
c. C3b
d. C5a

A

C5a

38
Q

Neutrophils are formed in the ________________precursor cell line.

A

Myeloid

39
Q

IgA, IgG, and IgD are different ___________ of antibodies.

A

Isotypes

40
Q

A protein found on our skin called _____________kills Escherichia coli on contact.

A

Psoriasin

41
Q

The complement cascade can kill pathogens by forming a pore called ________________.

A

MAC

Immunology Quiz Questions (15 decks)

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