Exam 1 (CH 1-5 And 7) Flashcards
Intrinsic drugs
Hormones, enzymes, growth factors
Extrinsic drugs
Outside factors (I.e: drugs) that produce identical effects to intrinsic drugs
When do you give drugs to pregnant woman
When the benefit out weighs the risk
3 drug names
Chemical- chemical composition
generic- 1st letter not capitalized, given by US adopted names council, short name
Brand- “trade/proprietary “ 1st letter capitalized, given by drug company
What is PINCH and what does it stand for
High alert drugs
P- potassium I- insulin N- arcotics C- chemo products H- eparin (anticoags)
Herbal product warnings
May interfere with pts prescribed meds
Agonist
Enhances a drugs effects
Antagonists
Blocks a drugs effect
Pharmacodynamics
Drug on body
Pharmacokinetics
Body’s effect on drugs A- bsorption D- istribution M- metabolism E- xcretion
What constitutes a true allergic reaction?
The bodies release of antihistamine and inflammation
AKA: anaphylaxis
MEC
Minimum effective concentration
: minimum amount of a drug in blood to cause intended reaction
Steady state
Continuous balance of drug entry and exit
Half life
Time needed for 1/2 of the drug to be eliminated from the body
Paradoxical drugs
Drugs that cause opposite responses in children than adult
Vital organ to metabolism
Liver
Vital organ to elimination
Kidneys
Teratogenic drugs
Drugs that cause birth defects
Pregnancy categories
A, B, C, D, (X)
8 pt rights
Right patient Right drugs Right dose Right route Right time Right documentation Right diagnosis Right response
Who can prescribe meds
Physicians Practitioners Dentists Podiatrist PAs
Standing order
Prescription on a regular basis
Single dose order
Order given only once
STAT
Order given immediately 1 time
PRN order
As needed order but still has a schedule to give
What are nurses in reference to drug administration
The final defense for detecting and preventing drug errors
Best way to prevent drug errors
medication reconciliations
5 steps
How many times should a calculation be checked?
Twice once by you and by a co worker
Principles of drug administration
Know PT history, Allergies Past ADR LAB VALUES AND ANY changes in condition
Enteral route entrance
Though GI tract by oral, NG or rectal
What do you have to make sure when administering enterally
If pt can swallow
Enteral route rate of absorption and commonality
Slowest absorption because it has to pass GI system.
Most commonly given
When taking oral enteral drugs what do you do to the pt
Have them sit up right, test if they can swallow, have them finish the full glass of water
Feeding tube types
NG nasogastric
PEG percutaneous endoscopic gastrostomy
NG tube precautions
Take sure that there is no CO2 tidal wave because that means tube is in lung and not stomach, hold med
Rectal considerations
Absorption affected by diarrhea
Do SIMS pose
Lay for 20 minutes
Parentral routes
ID, SC, IV, IM
Dump ID info
Injected between layers of skin Sites: inner forearm Common uses: TB test Volume: 0.01- 0.1 Needle size: 3/8 in Gauge: 25 Angle: 15
Dump SQ info
Between skin and muscle Sites: upper arm, abdomen Common uses: insulin/ heparin Volume: 0.5 - 1.0 mL Needle size: 3/8 in Gauge: 25-27 Angle: 45 ( 90 in obese)
Dump IV info
In vein Fastest and most dangerous form of admin Rapid absorption Sites: vein Given by IVP ( intravenous push) IVPB ( intravenous piggyback)
Dump IM info
In muscle Sites: deltoid (arm), ventrogluteal, vastus lateralis (knee) Volume: 1-3 mL Needle size: 1-1.5 in Gauge: 20-22 Angle: 90
Percutaneous route absorbed by and ways to administer
Absorbed by mucous membranes
Topical/ transdermal - don’t shave skin, thin layer Buccal Sublingual Ear drops Nose drops Spray Suppositories( vaginal)