EX1- Leys Flashcards
DNA that enters a bacterial cell can be _____, ____, or _____
- Degraded
- Integrated into the host chromosome
- Integrated into a plasmid (extrachromosomal element)
_______ are used by bacteria to degrade foreign DNA
Restriction endonucleases (restriction enzymes)
______ is the uptake of naked DNA by “complement cells.”
Transformation
_____ is the transfer of DNA between bacteria through a virus
Transduction
______ is the transfer of DNA through cell to cell contact using a sex pilus
Conjugation
Mutations in DNA can cause _________
antibiotic resistance
______ can be the result of base changes, deletions, insertions,duplications, or rearrrangements
Mutations
What type of mutation is less likely to cause antibiotic resistance?
Deletions
Different bacteria occupy different _________ in the oral cavity
environmental niches
Subgingival bacteria are generally _________
proteolitic
Supragingival bacteria are generally _______
saccrolitic
What factors promote colonization in the oral cavity?
- adherence properties
- synergistic bacteria
- nutritional substrates
- temperature
- moisture content
What are the factors that inhibit colonization in the oral cavity?
- antimicrobial properties of saliva
- mechanical shearing
- antagonistic bacteria
There are _____ bacterial species that are associated with periodontitis, while ____ species are associated with periodontal health
many, fewer
Shifts in microbial composition occur in _____, however no bacterium is found in all patients with ______ and never found in healthy subjects
periodontitis
The tissue destruction that occurs during periodontitis is mainly the result of a _______
host response
There is a small shift from gram _____ to gram ____ during periodontitis
positive, negative
The complexity of the microbial community ______ during periodontal disease
increases
There is a slight shift to more _______ bacteria in periodontitis
uncultivated
Microbial diversity _____ in caries
declines
There is a progression of ________ as caries progresses
dominant species
Each location in the oral cavity has its own associated microbial composition, however there is _______
overlap of species
What are the 3 methods for the introduction of DNA into bacteria?
- Transformation
- Transduction
- Conjugation