EX 1- Innate Defenses at Mucosal Surfaces- Bailey Flashcards
Surface that interacts with air that has associated glands for secreting mucus
Mucosal surface
How do most pathogens enter into the body?
Mucosal surfaces
What are the defenses of mucosal surfaces?
- Innate Immunity
- Adaptive Immunity
- Nonspecific barrier defenses
What are the 4 mucosal surfaces for gram negative pathogens?
- Oral cavity
- Respiratory tract
- reproductive/urinary tract
- GI tract
What are the “seven F’s” for transmission of gram negative mucosal pathogens?
Food, Feces, Fluids, Fingers, Flies, Fomites, Fornication
The size of a colony of bacteria that is required to cause disease
Inoculum
The inoculum size of shigella is as few as ____ organisms
50-100
What are the three barrier defenses that our body has against gram negative pathogens?
- Natural barrier defenses
- Innate Immunity
- Adaptive Immunity
What are the types of natural barrier defenses against gram negative bacteria?
- Secretory substances
- Anatomical and physiological barriers
- Indigenous microbiota
What are the 4 types of natural anatomical and physiological properties assisting with creating a physical barrier?
- Acidity (1-2 to 9)
- Motility (flushes bacteria away)
- Mucous layer and underlying glycocalyx
- Tight junctions
