Everything Flashcards
Gold standard to diagnose coeliac
Endoscopic intestinal biopsy
Drug class that reduces lithium excretion and increases toxicity
AT ii receptor blockers (losartan), ACEi, NSAIDs
Lithium uses
Mood stabilising - bipolar
Features lithium toxicity
Coarse tremor, hyperreflexia, confusion, polyuria, seizure
How many weeks before chronic pain
12
Chronic pain tx
gabapentin or amitriptyline
Cause of unilateral cleft lip
Incomplete fusion of nasolabial muscle rings
Function of
Activates vit D which increases phosphate absorption in GIT which increases serum phosphate
first line treatment to reduce stroke risk in af
DOACs - endoxaban
Familial adenomatous polyposis
Mutation of APC gene, causes colonic ademonas
MYH associated polyposis
Biallelic mutation of mutation Y
Colonic polyps
Later onset right sided cancers
Associated with breast cancer risk
Peutz-Jegher’s syndrome
STK11 mutation on chromosome 19
Benign intestinal hamartomas
Increase risk of GI, breast, ovarian cancers
Pigmantation pattern
Cowden disease
Mutation of PTEN on ch10q22
Macrocephaly
Intestinal hamartomas and trichilemmomas
Increase risk of thyroid and breast cancer
Lynch syndrome
DNA mismatch repair gene mutation
colorectal and endometrial cancer
Right sided mutinous colonic tumours
Investigating osteomyelitis
MRI
Managing osteomyelitis
Flucloxacillin and surgical debridement
How is hep c spread
Parenteral
Sexual
vertical;
Needlestick injuries
The L rule for haemoglobin graph
Shifts to L (lower oxygen delivery) by
Low H+
Low pco2
Low 2,3-DPG
Low temp
The L rule for haemoglobin graph
Shifts to L (lower oxygen delivery) by
Low H+
Low pco2
Low 2,3-DPG
Low temp
Acute myeloid leukaemia blood results
Low neutrophils
High WBC
Blood supply to Meckel’s diverticulum
Vitelline artery
Superficial inguinal lymph nodes
Anal canal below pectinate line
Perineum
Thigh
Penis
Scrotum
Vagina
Deep inguinal lymph nodes
Gland penis
Para-aortic lymph nodes
Testes
Ovaries
Kidneys
Adrenal
Axillary lymph nodes
Lateral breast
Upper limb
Internal iliac lymph nodes
Anal canal below pectinate line
Lower rectum
Cervix + inferior uterus
Superior mesenteric lymph nodes
Duodenum
Jejunum
Inferior mesenteric lymph nodes
Descending colon
Sigmoig colon
Upper rectum
Coeliac lymph nodes
Stomach
Major source of IL-1
Macrophage
What do the granules of neutrophils contain?
Myeloperoxidase and lysozyme
What do the granules of basophils contain?
Histamine and hpeparin
Mast cell granule contents
Heparin and histamine
ECG changes V1-4
LAD
ECG changes II, III and aVF
RCA
ECG changes V4-6, I and aVL
LAD or LCX
Mitral regurgitation on stethoscope
Soft s1
What is type 1 diabetes mellitus?
Autoimmune disorder where B cells in Islets of Langerhans are attacked by immune system
What is type 2 diabetes mellitus
Too much adipose tissue = not enough insulin
Risk factors for endometrial cancer
PCOS
Obesity
Features of endometrial cancwr
Post-menopausal bleeding
ACEi side effects
Angioedema
Cranial nerve supplying sternocleidomastoid and deltoid
CN11
Lesion to CN11
Head turns contralateral side
Side effects B-blockers
Bronchospasm
Cold peripheries
Erectile dysfunction
Nerve damaged when object lodges in piriform recess
Internal laryngeal
Genital tubercle forms
Glans penis
Corpus cavernosum and spongiosum
Glans clitoris
Vestibular bulbs
Urogenital sinus forms
Bulbourethral glands
Prostate gland
Bartholin glands
Skene glands
urogenital folds
Ventral shaft of penis
Labia minora
Labioscrotal swelling
Scrotum
Labia majora
Mesonephric duct forms
Seminal vesicles
Epididymis
Ejaculatory duct
Ductus deferens
Paramesonephric duct forms
Fallopian tubes
Uterus
Upper third of vagina
Most common cause of PID
Chlamydia trachomatis
Sx PID
Lower abdo pain
Fever
Deep dyapareunia
Dysuria
Vaginal/cervical discharge
treatment for osteomyelitis
clindamycin
antibiotics impacting nucleic acid synthesis
ANTHONY QUINN = anti-folate (trimethoprim) and quinolones
ABx impacting protein synthesis
MC FAT
Macrolides, chloramphenicol, fusific acid, ahminoglycosides, tetracyclines
gram +ve cocci
staphylococcus and strep
gram -ve cocci
meningitis and gonorrhoea
gram +ve bacilli
anthrax, bacillus, clostridium, diphtheria
ABx impacting cell wall synthesis
PENNY VAN CEPH
penicillin, vancomycin and cephalosporins
inheritance pattern more common in first cousins
autosomal recessive
most common complication of appendectomy
pelvic abscess
most common cause of gastroenteritis
norovirus
treatment for delirium tremens
benzo - diazepam
which individuals can be affected by x-linked recessive disease?
mother to son transmission
OR daughter with Turner’s - only one X chromosome
e.g. x-linked recessive conditions
haemophilia, G6PD, muscular dystrophy
what is a film’s tumour?
what is a film’s tumour?