Everything Flashcards

1
Q

Gold standard to diagnose coeliac

A

Endoscopic intestinal biopsy

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2
Q

Drug class that reduces lithium excretion and increases toxicity

A

AT ii receptor blockers (losartan), ACEi, NSAIDs

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3
Q

Lithium uses

A

Mood stabilising - bipolar

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4
Q

Features lithium toxicity

A

Coarse tremor, hyperreflexia, confusion, polyuria, seizure

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5
Q

How many weeks before chronic pain

A

12

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6
Q

Chronic pain tx

A

gabapentin or amitriptyline

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7
Q

Cause of unilateral cleft lip

A

Incomplete fusion of nasolabial muscle rings

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8
Q

Function of

A

Activates vit D which increases phosphate absorption in GIT which increases serum phosphate

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9
Q

first line treatment to reduce stroke risk in af

A

DOACs - endoxaban

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10
Q

Familial adenomatous polyposis

A

Mutation of APC gene, causes colonic ademonas

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11
Q

MYH associated polyposis

A

Biallelic mutation of mutation Y
Colonic polyps
Later onset right sided cancers
Associated with breast cancer risk

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12
Q

Peutz-Jegher’s syndrome

A

STK11 mutation on chromosome 19
Benign intestinal hamartomas
Increase risk of GI, breast, ovarian cancers
Pigmantation pattern

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13
Q

Cowden disease

A

Mutation of PTEN on ch10q22
Macrocephaly
Intestinal hamartomas and trichilemmomas
Increase risk of thyroid and breast cancer

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14
Q

Lynch syndrome

A

DNA mismatch repair gene mutation

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15
Q

colorectal and endometrial cancer
Right sided mutinous colonic tumours

A
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16
Q

Investigating osteomyelitis

A

MRI

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17
Q

Managing osteomyelitis

A

Flucloxacillin and surgical debridement

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18
Q

How is hep c spread

A

Parenteral
Sexual
vertical;
Needlestick injuries

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19
Q

The L rule for haemoglobin graph

A

Shifts to L (lower oxygen delivery) by
Low H+
Low pco2
Low 2,3-DPG
Low temp

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19
Q

The L rule for haemoglobin graph

A

Shifts to L (lower oxygen delivery) by
Low H+
Low pco2
Low 2,3-DPG
Low temp

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20
Q

Acute myeloid leukaemia blood results

A

Low neutrophils
High WBC

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21
Q

Blood supply to Meckel’s diverticulum

A

Vitelline artery

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22
Q

Superficial inguinal lymph nodes

A

Anal canal below pectinate line
Perineum
Thigh
Penis
Scrotum
Vagina

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23
Q

Deep inguinal lymph nodes

A

Gland penis

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24
Para-aortic lymph nodes
Testes Ovaries Kidneys Adrenal
25
Axillary lymph nodes
Lateral breast Upper limb
26
Internal iliac lymph nodes
Anal canal below pectinate line Lower rectum Cervix + inferior uterus
27
Superior mesenteric lymph nodes
Duodenum Jejunum
28
Inferior mesenteric lymph nodes
Descending colon Sigmoig colon Upper rectum
29
Coeliac lymph nodes
Stomach
30
Major source of IL-1
Macrophage
31
What do the granules of neutrophils contain?
Myeloperoxidase and lysozyme
32
What do the granules of basophils contain?
Histamine and hpeparin
33
Mast cell granule contents
Heparin and histamine
34
ECG changes V1-4
LAD
35
ECG changes II, III and aVF
RCA
36
ECG changes V4-6, I and aVL
LAD or LCX
37
Mitral regurgitation on stethoscope
Soft s1
38
What is type 1 diabetes mellitus?
Autoimmune disorder where B cells in Islets of Langerhans are attacked by immune system
39
What is type 2 diabetes mellitus
Too much adipose tissue = not enough insulin
40
Risk factors for endometrial cancer
PCOS Obesity
41
Features of endometrial cancwr
Post-menopausal bleeding
42
ACEi side effects
Angioedema
43
Cranial nerve supplying sternocleidomastoid and deltoid
CN11
44
Lesion to CN11
Head turns contralateral side
45
Side effects B-blockers
Bronchospasm Cold peripheries Erectile dysfunction
46
Nerve damaged when object lodges in piriform recess
Internal laryngeal
47
Genital tubercle forms
Glans penis Corpus cavernosum and spongiosum Glans clitoris Vestibular bulbs
48
Urogenital sinus forms
Bulbourethral glands Prostate gland Bartholin glands Skene glands
49
urogenital folds
Ventral shaft of penis Labia minora
50
Labioscrotal swelling
Scrotum Labia majora
51
Mesonephric duct forms
Seminal vesicles Epididymis Ejaculatory duct Ductus deferens
52
Paramesonephric duct forms
Fallopian tubes Uterus Upper third of vagina
53
Most common cause of PID
Chlamydia trachomatis
54
Sx PID
Lower abdo pain Fever Deep dyapareunia Dysuria Vaginal/cervical discharge
55
treatment for osteomyelitis
clindamycin
56
antibiotics impacting nucleic acid synthesis
ANTHONY QUINN = anti-folate (trimethoprim) and quinolones
57
ABx impacting protein synthesis
MC FAT Macrolides, chloramphenicol, fusific acid, ahminoglycosides, tetracyclines
58
gram +ve cocci
staphylococcus and strep
59
gram -ve cocci
meningitis and gonorrhoea
60
gram +ve bacilli
anthrax, bacillus, clostridium, diphtheria
61
ABx impacting cell wall synthesis
PENNY VAN CEPH penicillin, vancomycin and cephalosporins
62
inheritance pattern more common in first cousins
autosomal recessive
63
most common complication of appendectomy
pelvic abscess
64
most common cause of gastroenteritis
norovirus
65
treatment for delirium tremens
benzo - diazepam
66
which individuals can be affected by x-linked recessive disease?
mother to son transmission OR daughter with Turner's - only one X chromosome
67
e.g. x-linked recessive conditions
haemophilia, G6PD, muscular dystrophy
68
what is a film's tumour?
69
what is a film's tumour?