10/10 Flashcards
types of generalised seizure
tonic clonic, myoclonic, absence
types of focal seizure
aware/impaired awareness
mx generalised seizure
lamotrigine/levetiracetam
mx absence seizure
ethosuximide
mx focal seizure
carbimazole
sx MS
visual changes, foot drag, spasticity
sx Guillain barre
progressive neuropathy, weakness, paraethesia
mx Guillain barre
IVIG
pathophys myasthenia gravis
AB mediated autoimmune disease against nAChR at NMJ
sx myasthenia graves
ptosis, diplopia
mx myasthenia graves
pyridostigmine
pathophys normal pressure hydrocephalus
hydrocephalus sx without raised CSF
sx normal pressure hydrocephalus
gait dyspraxia, cognitive impairment, urinary incontinence
mx normal pressure hydrocephalus
ventriculoperitoneal shunting
what is corticobasal degeneration
tau deposition
sx corticobasal degeneration
asymmetrical rigidity, apraxia, sensory loss
‘Micky mouse ears’ on MRI
progressive supra nuclear palsy
sx progressive supranuclear palsy
backward falls, supra nuclear gaze palsy, dysphasia
posterior cerebral artery stroke affects
eyesight
mx ischaemic stroke <4h
thrombolysis with alteplase, thrombectomy <6h
mx ischaemic stroke >4h
300mg aspirin 2w, switch to 75mg clopidogrel
mx Alzheimer’s
acetylcholinesterase inhibitors e.g. donepezil
anti-voltage gated calcium channels
Lambert eaton
auto-antibodies against post-synaptic acetylcholine receptors
myasthenia graves
substantia nigra is affected in….
parkinson’s = degraded dopamine neurone
mx eczema
emollient and increase the strength of steroid depending on severity
mx acne
mild: 2 of: benzoyl peroxide/ABx/retinoid
Mod-sev: retinoid/COCP/ABx
diagnosing diabetes if sx
one test is enough - random >11, fasting >7, HbA1C >48
diagnosing diabetes if asx
2 tests needed - random >11, fasting >7, HbA1C >48
mx diabetes
metformin mono - duo with pioglitazone, DPP4-i, sulfonylurea -> trio -> insulin
mx hyperthyroidism
anti-thyroid like carbimazole/propylthiouracil
mx hyperthyroidism in pregnancy
propylthiouracil in tri1-> carbemazole