Epithelium Flashcards
Two sides of Epithelium
Apical Basolateral
Characteristics of Epithelium
PARCA Polar Avascular Attached Regeneration Cellularity (cell junctions)
Cellularity (in Epithelial cells)
Occluding (Tight) junctions (Zonulae occludens)
Prevents passage of water and solutes
Prevents enzymes and wastes in the lumen at the apical surface to reach the basolateral surface.
Linking the cytoskeletons of adjacent cells and stabilizing tight junctions
Gap junctions
allow rapid communication
Held together by channel proteins (junctional proteins, connexons)
Allow ions to pass
Coordinate contractions in heart muscle
Desmosome (anchoring junctions)
allow mechanical stress
Provides strength to epithelium laterally and basally
Tight junctions
Lipid portion of the membrane bound, Prevent entry, Apical surface of the intestinal lumen
Gap Junctions
Transmembrane bound, Allow communication, Cardiac muscle
Desmosome
Adhesion molecules proteoglycan and cytoskeleton bound,Maintain the strength, Skin
Between cardiac muscle cells
Polarity
Apical surfaces: Microvilli increase absorption or secretion Cilia (ciliated epithelium) move fluid Basal surfaces Cell to extracellular matrix Lateral surfaces Occluding junction Anchoring Communication
Structure of Microvilli
Simple Surface Area
Structure of Cilia
Stratified or pseudo stratified
Attachment to Basalir Lamina
Clear layer (Lamina lucida) Thin layer Secreted by epithelia Barrier to proteins Dense layer (Lamina densa) Thick fibers Produced by connective tissue Strength and filtration
Amount of Insensible Persperation
500 mL
Avascularity of Epithelial Cells
Epithelial cells derive support by diffusion from blood vessels in underlying connective tissue
Thickness of epithelia cannot be greater than the distance over which nutrients can diffuse from vascular source.
Our skin is covered by epithelium. And each day, we lose about 500 ml of water via Insensible Perspiration.
In what situation do we need to worry about insensible perspiration?
Regeneration of Epithelial
Epithelia are replaced by division of germinative cells (stem cells)
Near basal lamina
Layers of Epithelium
Come (corny) Lets (lucidum) Get (Granulosum) Sun (spinosum) Ger (Germinativum) Burned (Basal)
Simple/Stratified Cuboidal
Simple cuboidal epithelium Secretion and absorption (kidneys) Ducts Stratified cuboidal epithelia Sweat ducts and mammary ducts