Ebryology Flashcards
p arm
smaller top arm
q arm
lower, larger arm
chromosomes held together by
centrosomes
number of autosomes
22
all somatic cells have the cell cycle:
G1,S,G2 Mitosis, cytokinesis, G0
mitosis phases
pmat
gametogenesis
spermatozoa, oocyte
gaemtogensis does not make ____ it makes ____
diploid cells, haploid
manifestations of an irregular karyotype
trisomy 21: crease on hand, sloped forehead, etc trisomy 13 (not viable) monosomy "turner's syndrome" wet neck, short, cardiovascular disease, synthetically provide hormones
structural malformations
parts of chromosome to be missing, deformed:
cri-du-chat, angelman syndrome, prader-will syndrome
nearly ___ of congenital malformations are due to unknown causes
50%
all somatic cells are ______
diploid (2n)
______ phases of gamete formation
origin and migration,
______ phase of germ cells is the same
migration or origin, proliferation of germ cells through mitosis
phase 1
origin and migration of germ cells
phase 2
proliferation of germ cells through mitosis (puberty for men, first 5 months of development for women)
follicle is made of
prophase and epithelium combined to surround oocyte (primary oocyte)
meiotic event in ovum for priomordial follicle
primary oocyte
final step of meiosis is not complete until
conception
Hormonal Control of Ovulation
GnRH, FSH, LH
GnRH is released from
Hypothalamus
GnRH acts on the
Anterior pituitary
ANt pit secretes
FSH, LH
Corpus luteum secretes
progesterone
spermatogensis located in
seminiferous tubule
smallest cell in body
sperm
acrosome is made by shifting
golgi apparatus to head
increases in LH stimulates
Laydig cells to
fertilization occurs in the ____ or the uterine tube
ampulla
Capacitation
to fully mature, the sperm need to live in the uterus, to dissolve acrosome, and utilize mitochondria
requires approx _____ for capacitation
5-7 hours
corona radiata was originally
granulosa cite
acrosome reaction
spermatozoa penetrate the corona radiata and zona pellucida
prevention of polyspermy
automatically depolarizes cell wall
polyspermy is prevented by an influx of
Ca2+
cleavage
4 days until morula
individual cells called
blastomeres
____of structure doesn’t increase, only the _____
size, number
zona palucida is a ____ shell
hard (Calcified)
from morula to blastula
compaction, differentiation, cavitation
blastocyst formation includes the formation of _____
sodium potassium pumps
inner cell mass structures become___
embryo
RNA in zygote is originally__
all maternal
Maternal-Zygotic transition causes a _______ in RNA
drop
Pluripotent cell example:
Inner mass cells
Totipotent cell example:
morula
AS cells are either ____ or ______
multipotent or unipotent
Day 6-7 the zygote;
breaks out of shell and embeds in uterine wall
implantation includes the
trophoblast begins to penetrate between the epithelial cells of the uterine mucosa
when does pregnancy begin?
implantation, also no longer capable of bein totipotent
all three germ layers are made of ______ and push the ____ out of the way
epiblast hypoblast
the _____ is formed by the mesoderm cells
notochord
the notochord is formed by the ______ migrating through the ________
mesoderm/primitive node
ectoderm
surface ectoderm; neuroectoderm
prosencephalon
3
mesencephalon
4
rhombencephalon
5
somite organization
basis of forming axial skeleton
segmentation is conserved by _______ genes
HOX genes (allow the body to be segmented in the appropriate way)
placenta
chorion
primary stem villus
11 to 13 days as cytotrophoblastic proliferations that bud into the overlying ; cytotrophoblast and syncytiotrophoblast
secondary stem villus
day 16 the extraembryonic mesoderm begins to proliferate
3 phases of human development
germinal embryonic, fetal
phase in which fetus is most susceptible to …..
embryonic