Endocrine System Flashcards

1
Q

endocrine system characteristics

A
  • has ductless glands and composed of endocrine tissues

- secretes hormones into blood

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2
Q

target cells

A

any cell w/ receptor for specific hormone

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3
Q

hormone classes

A

steroid hormone, hormones derived from amino acids & peptide+protein hormones

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4
Q

steroid hormones

A
  • derived from cholesterol

- has lipids: hydrophobic, lipid soluble

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5
Q

hormones derived from amino acids

A
  • tyrosine: amino acids used to make thyroid hormones (T4)

- tryptophan: amino acid makes serotonin + melatonin

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6
Q

peptide & protein hormones

A
  • from chains of amino acids
  • hydrophilic, water soluble
  • ex: oxytocin + growth hormone
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7
Q

pituitary glands characteristics

A
  • suspended by hypothalamus
  • located at sella turcica o sphenoid bone
  • highly vascular (allows secretions of hormones)
  • composed of the anterior + posterior pituitary
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8
Q

what secretes from the hypothalamus?

A

regulating hormones are secreted

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9
Q

what do the regulating hormones do?

A

regulate the secretion of hormones from the pituitary gland

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10
Q

anterior pituitary gland function

A

secretes hormones that affect growth, metabolism + reproduction

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11
Q

hormones anterior pituitary gland secrets:

A
  • follicle stimulating hormone (FSH): reproduction
  • leutinizing hormone (LH): reproduction
  • adrenocorticotropic hormone (ACTH): stimulates secretion of steroids from adrenal glandss
  • thyroid stimulating hormone (TSH): stimulates secretion of thyroid
  • prolactin (PRL): milk formation
  • growth hormone (GH): growth + metabolism
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12
Q

posterior pituitary gland

A
  • ext. of hypothalamus formed from nervous tissue

- secretes hormones produced in hypothalamus

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13
Q

hormones posterior pituitary gland secretes:

A
  • oxytocin: stimulates uterine contractions

- antidieuretic hormone (ADH): vasopressin–stimulates water reabsorption in kidney

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14
Q

thyroid gland characteristics

A
  • located on superior surface of trachea below larynx
  • shaped like butterfly
  • composed of 2 diff cells (follicles + parafollicular)
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15
Q

thyroid gland cell types follicles:

A
  • follicular epithelial cells
  • produce thyroxine (T4) hormone
  • controls metabolism, growth + development
  • produced in lumen of gland + secreted from follicular cells
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16
Q

thyroid gland cell types parafollicular cells:

A
  • surround follicle

- secrete calcitonin

17
Q

what does calcitonin do?

A
  • stimulates calcium uptake by bone, decreasing plasma calcium
  • builds bone matrix (osteoblasts)
18
Q

parathyroid gland

A
  • consists of 4 glands on posterior surface of thyroid gland

- produces parathyroid hormone (PTH)

19
Q

functions of PTH

A
  • acts to increase calcium levels

- stimulates breakdown of bone matrix (osteoclasts)

20
Q

how can PTH increase calcium levels?

A
  • decreasing calcium excretion from kidney

- increasing vitamin D activation in kidney

21
Q

function of vitamin D

A

increase calcium reabsorption in intestine

22
Q

adrenal gland basic characteristics

A
  • located on superior surface of kidney

- 2 glands (adrenal cortex + adrenal medulla)

23
Q

adrenal cortex

A
  • secretes steroid hormones

- 3 layers (zona glomerulosa, fasciculata, reticularis)

24
Q

zona glomerulosa

A
  • secretes mineralocorticoids: predominantly aldosterone (regulates salt balance)
25
Q

zona fasciculata

A
  • secrets glucocorticoids: predominantly cortisol (regulates stress response)
26
Q

zona reticularis

A
  • secretes androgens: small amounts of testosterone
27
Q

testosterone functions

A
  • female sex drive converted to estrogen in both male and female
28
Q

adrenal medulla

A
  • produce epinephrine (80%) & norepinephrine (20%)

- help body combat short term stress (fight or flight response)

29
Q

endocrine tissues

A
  • found in organs that have additional functions (diff primary function)
  • pancreas, hypothalamus, gonads
30
Q

endocrine tissues: pancreas

A
  • endocrine part called Islets of Langerhans
  • ALPHA CELLS: secrete glucagon
  • BETA CELLS: secrete insulin
31
Q

glucagon

A
  • increase blood glucose during hypoglycemic state

- secreted by alpha cells

32
Q

insulin

A
  • decrease blood glucose during hyperglycemic state

- secreted by beta cells

33
Q

endocrine tissues: hypothalamus

A
  • 3 endocrine functions
    1) PRODUCE REGULATORY HORMONES [stimulate/inhibit release of hormones]
    2) SYNTHESIZE HORMONES from P pituitary
    3) NERVOUS FUNCTION: controls body temp, thirst, urine output, hunger, daily rhythms + behavioural patterns
34
Q

endocrine tissues: gonads

A
  • OVARIES: primary + secondary follicles secrete estrogen & corpus luteum secrete estrogen + progesterone
  • TESTES: Leydig cells secrete testosterone
35
Q

endocrine tissues: other

A
  • digestive tract: secretin
  • heart: atrial natriuretic peptide
  • kidney: renin
  • placenta: estrogen, progesterone, human chorionic gonadotropin