endocrine system Flashcards

1
Q

chemical messengers, bind to target cells with specific receptors. part of the endocrine system

A

hormones

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2
Q

the ___ controls processes that take a while, controls actions of the body

A

endorcrine system

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3
Q

hormones are secreted through

A

exocrine glands

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4
Q

what are the types of receptors hormones act through?

A

-membrane receptors: cell membrane
-nuclear receptors: nuclear membrane
-cytoplasmic receptors: cytoplasm of organelles

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5
Q

target cells must have ____ for hormones to affect them

A

specific receptors

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6
Q

thyroid hormone receptors

A

membrane receptors and nuclear/cytoplasmic receptors

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7
Q

describe the process of thyroid hormones binding to their receptors on a target cell

A
  1. thyroid hormones bind to a membrane receptor and are transported into the cell by active transport using ATP
  2. bind to cytoplasmic or nuclear receptors- hormone complex; gene regulatory protein
  3. transport to the nucleus to alter gene expression
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8
Q

describe the process of steroid hormones binding to their receptors on a target cell

A

1.steroid hormones, estrogen and testosterone, are lipid soluble and can diffuse through cell membranes
2. hormone can end up in the cytoplasm or nucleus, meets a gene regulatory protein
4. ultimate site of activity is in the nucleus.

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9
Q

what is a gene regulatory protein

A

activates or inhibits specific genes

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10
Q

why is the second messenger system needed

A

some hormones can be too large, too polar, or charged to pass across a cell membrane

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11
Q

describe the second messenger system

A
  1. first messenger: hormone binds to a transmembrane protein that act as membrane receptors on the surface of target cells, activates second messenger -uses ATP
  2. second messenger system: in the cytoplasm, the second messenger ex. cAMP, activates kinase
  3. kinase activates or inactivates enzymes that modify the direction and rate of cellular activity; phosphorylates
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12
Q

hormone functions

A

*influence cellular functions by altering rates of biochemical processes
-affect enzyme activity and alter cell metabolism
-change membrane permeability
-regulate synthesis of proteins
-stimulate release of hormones from other glands

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13
Q

hormones are regulated by

A

-rate of secretion
-activation and inactivation rates

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14
Q

hormones need to receive info of its levels in the ___

A

plasma

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15
Q

negative feedback

A

rising levels of on hormone decreases the secretion of another

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16
Q

output escalates rather than remaining around a set point

A

positive feedback