endocrine anatomy Flashcards

1
Q

pituitary gland is situated

A

in the sella turcica (pituitary fossa) of the sphenoid bone

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2
Q

crinoid processes

A

4 processes making a 4 poster bed like shape around the pituitary gland

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3
Q

hypothalamic hypophyseal tract

A

connects neutrons of hypothalamic nuclei to their release site n the posterior pituitary

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4
Q

portal venous system of the pituitary gland

A

connecting the venous dranage of the hypothalamus to the pituitary gland

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5
Q

colloid filled space in the pituitary gland

A

remnant of rathke’s pouch

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6
Q

anterior pituitary

A

glandular tissue

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7
Q

pars nervosa is closer to

A

posterior pituitary

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8
Q

posterior pituitary is connected to the hypothalamus via

A

infundibulum

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9
Q

pars tuberalis

A

wrapped around the infundibulum

delivers higher degree of vasculature through the pituitary stalk

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10
Q

cells in pars tubralis

A

basophilic

secrete ACTH, FSH, LH

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11
Q

pars tuberalis brings vasculature to

A

the infundibulum

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12
Q

pars distalis

A

acidophils - secrete GH and prolactin

basophils - secretion ACTH, FSH, LH, TSH

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13
Q

pars distalis closer to

A

anterior pituitary

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14
Q

pars intermedia

A

mostly basophils

secrete malanocyte simulating hormone (chromophobe cells, meaning cytoplasm is clear)

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15
Q

neurohyphysis

A

posterior pituitary

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16
Q

posterior pituitary stores

A

anti-diuretic hormone and oxytocin which are synthesised in the hypothalamus

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17
Q

ADH synthesised in

A

supraoptic nucleus of the hypothalamus

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18
Q

Oxytocin synthesised in

A

paraventricular nucleus

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19
Q

herring bodies

A

swollen nerve terminals that are full of either ADH or oxytocin

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20
Q

what stimulates release of herring body contents

A

pituicytes

21
Q

pinealocytes

A

large cells with pale round nuclei surrounded by pale cytoplasm
secrete melatonin rhythmically (circadian rhythm)

22
Q

astrocytes

A

star shaped glial cells wth very dark nuclei

maintenance cell

23
Q

brain sand

A

corpora arenacea

composition of calcium and magnesium salts

24
Q

thyroid glad is two lobes connected by

A

an isthmus

25
superior and middle thyroid veins drain to
internal jugular vein
26
inferior thyroid vein
JV or brachiocephalic
27
external carotid supplies
superior thyroid arteries
28
sabclavians supply
inferior thyroid arteries
29
pain in the thyroid
parasympathetic component from vagus which carries visceral sensation
30
thyroid lobule
bunch of follicles | in a fascial capsule
31
thyroid follicles
storage lake full of thyroglobulin
32
TSH stimulates
follicular cells to ingest thyroglobulin via endocytes from the lake T3 and T4 are cleaved from thyroglobulin and released into blood stream
33
parafollicular cells
C cells grainy cells between follicles secrete calcitonin - acts by inhibiting osteoclasts which reduces serum calcium
34
chief cells secrete
parathyroid hormone
35
parathyroid hormone counters
calcitonin
36
PTH stimulates
stimulates osteoclast activity which raises serum calcium via bone resorption increases GIt absorption of calcium
37
oxyphillic cells
less abundant and often clustered only appear at 6-7yo and increase with age purpose unclear
38
adrenal glands are located
on top of the kidney | primary retroperitoneal
39
blood supply of the adrenal glands
paired adrenal arteries from abdomnal aorta | arteries supply the cortex first
40
drainage of the adrenal glands
drains in cortex to medulla direction | central adrenomedullary vein to the renal vein
41
the right adrenal gland can drain directly into
the IVC
42
innervation off the adrenal glands
sympathetics from the adrenocortcal ganglion | parasympathetics from the vagus nerve
43
medulla histology
large blood vessels centrally
44
chromaffin cells
light pale nuclleou, pale basophilic cytoplasm | synthesised and secrete adrenaline and noradenrealine
45
zona glomerulus
small curved cell columns, dark round nuclei spongy appearance secretes mineralocorticoids
46
zona fasciculata
roughly 3/4 of the Cortex radially oriented fascicle like tubes of cells separated by fenestrated capillaries very pale contents that appear spongy
47
zona recularis
``` branched cords of cells with sinusoidal space between smaller cells least spongy looking secretes androgens not fully present until 3yoo ```
48
PP cells
secrete pancreatic polypeptide unregulated gastric chief cells inhibits bile, pancreatic enzyme, bicarbonate secretions and intestine motility
49
what does pancreatic polypeptide do
unregulated gastric chief cells (pepsinogen secretion) | inhibits bile, pancreatic enzyme, bicarbonate secretions and intestine motility