development of the endocrine system Flashcards
pituitary gland develops in
rathe’s puch
rathke’s such made of
stomodeum and oropharyngeal membrane
stomodeum
invagination of surface ectoderm
posterior pituitary derived from
forebrain - neural tube ectoderm
fulll of neurones connected to hypothalamic neurons
anterior pituitary derived from
surface ecoderm of rathke’s pouch
glandular appearance
pineal gland
neurologically linked to retina’s photoreceptors
secretes melatonin to set the circadian rhythm
calcification of the pineal gland
can occur from 2 years old
melatonin inhibits hypothalamic GnRH secretion
precocious puberty associated with pineal tumours
origin of the thyroid
foramen caecum of the tongue
how does the thyroid migrate
through the tongue into the neck
through thyroglossal duct which later closes off
arrests inferior to thyroid cartilage
increase in TH in late fatal period stimulates development of
brown fat - mechanism for non-shivering thermgenesis
adrenal glands develop from
adrenal ridge
only cleaved from the gonad once primordial germ cells enter the gonad
medullar cells of the adrenal glands are formed from
neural crest cells
become chromaffin cells
specialised post synaptic autonomic nerve cells
pre-synaptic sympathetic nerves release ACh directly on chromaffin cells
synthesis and secrete adrenaline and noradrenaline
cortex develops from
LP-mesodern
2 waves
1. fetal cortex
2. definitive adult cortex
fetal adrenal gland
secrete DHEA
converted to estradiol by the placenta
regulated maturation of the lungs, GIT, and regulate partition and other perimaternal adaptations
definitive cortical cells
encapsulate the fetal cortex and the developing medulla
no zona reticularis in a feu s
