Eigenschappen neurodegeneratieve ziektes Flashcards

1
Q

Welke eiwitten aggregeren bij AD?

A

Amyloid-beta en Tau

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2
Q

Welke eiwitten aggregeren bij FD?

A

Tau en andere eiwitten

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3
Q

Welke eiwitten aggregeren bij PD?

A

Alfa synucleine en lewy-lichamen

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4
Q

Welke eiwitten aggregeren bij HD?

A

Huntingtin

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5
Q

Welke eiwitten aggregeren bij Lewy Body Dementia

A

Alfa synucleine en lewy-lichamen

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6
Q

Welke eiwitten aggregeren bij VD?

A

Geen! Deze ziekte is t.g.v. vasculaire scade

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7
Q

Welke eiwitten aggregeren t.g.v. Multiple Sclerose?

A

Myeline degenereerd juist! (dus niet aggregeren)

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8
Q

Wat is de primaire hersen regio dat is aangetast bij AD?

A

Hippocampus/cortex

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9
Q

Wat is de primaire hersen regio dat is aangetast bij FD?

A

Frontale en Temporale cortex

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10
Q

Wat is de primaire hersen regio dat is aangetast bij PD?

A

Substantia Nigra

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11
Q

Wat is de primaire hersen regio dat is aangetast bij HD?

A

Striatum/Basale ganglia

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12
Q

Wat is de primaire hersen regio dat is aangetast bij Lewy Body Dementia?

A

Hippocampus

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13
Q

Wat is de primaire hersen regio dat is aangetast bij Vanishing White Matter?

A

Corpus callosum en cerebellum

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14
Q

Wat is de primaire hersen regio dat is aangetast bij Multiple Sclerose?

A

Overal, zelfs in je ruggenmerg

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