EAR PHARMACOLOGY Flashcards

1
Q

What causes O. Externa?

A
  • pseudomonas
  • proteus
  • fungi-aspergillus
  • *gram neg rods
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2
Q

How do you tx O. Externa (2)?

A

decrease excessive moisture

  • acetic acid (vosol)
  • 50/50 isopropyl alcohol and white vinegar-3-5 drops x4-6 hrs

tx abx: fluoroquinolone drops (ciprofloxacin)

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3
Q

Vosol ADE:

A

transient burning stinging

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4
Q

Fluoroquinolone ADE:

A

fungal superinfection, pain pruritus

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5
Q

T/F TX with aminoglycosides for O Extrena is appropriate even if you cant see the TM

A

FALSE! Don’t give aminoglycosides,

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6
Q

Why is aminoglycoside tx inappropriate in perforated TM?

A

can cause vestibular ototoxicity

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7
Q

What causes infection in O. media?

A
  • Strep pneumo

- H flu

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8
Q

How do you tx O. media (2)?

A
  • high dose amoxicillin 80-90 mg/kg/day every 12 hrs

- augmentin 90 mg/kg/day QID x 12 hrs for 10 days

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9
Q

If patient is allergic to penicillin but did not have an anaphylactic rxn what is the next best tx option?

A

cefdinir cefpodoxime

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10
Q

What class of drugs are not given for ear infections due to high bacterial resistance?

A

Macrolides

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11
Q

When is it appropriate to observe pediatric patients with ear infections?

A

6-12 months:

  • unilateral pain
  • mild symptoms

2 y/o and older:
-uni or bilateral pain and mild symptoms

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12
Q

When is it abx tx necessary?

A

**patient is less than 6 months

  • *patient is less than 2 y/o with
  • severe pain
  • fever >102.2
  • bilateral AOM
  • pain more than 2-3 days
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13
Q

T/F Amoxicillin is tx of choice for initial dx of AOM and Augmentin in tx of choice after 48-72 observation with no improvement

A

TRUE

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14
Q

What pathogen causes bacterial sinusitis?

A

S.. pneumo, H flu M. catarrhalis

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15
Q

When would you prescribe abx for bacterial sinusitis?

A

if symptoms have been persistent for more than 10 days

-if symptoms worsen 5-7 days after visit

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16
Q

What is first line tx for bacterial sinusitis in adults?

A

Augmentin 500mg/125mg PO QID

17
Q

What is second line tx for bacterial sinusitis in adults?

A

3rd gen cephalosporin cefpodoxime 200mg daily

18
Q

What is tx for bacterial sinusitis if patient has IgE rxn to penicillin?

A

Doxycycline 100mg QID POP daily

19
Q

What abx (2) should you not prescribe for bacterial sinusitis?

A

Macrolides

TMP-SMX

20
Q

T/F Vaccination against influenza and pneumococcus reduces risk of O. media infection

A

True

21
Q

T/F The empiric abx of choice for acute sinusitis and O. media is amoxicillin

A

True

22
Q

T/F The empiric drug of choice for acute pharyngitis is penicillin

A

True

23
Q

What is first line tx for O media in children? second line txif allergic to mild penicillin allergy?

A

1st: augmentin 45 mg/kg/day PO QID
2nd: Clindamycin and cefpodoxime