E3: Vac Flashcards
name the 5 vac types
whole pathogens
subunits
particle-based
vectored
nucleic acid
name the vac type:
contains macromolecules of a pathogen, not the whole pathogen
subunit
name the type
contains PLB membranes, containing DNA from the pathogen
Vectored
contains bacteria and VLP (virus-like particles)
Particle-based
contains mRNA
nucleic acids
can be either attenuated or inactivated
whole pathogen
name the vac type from these pros
retain replication ability, activating humoral and c-mediated response
no boosters
attenuated
name the vac type from these pros
similar to inactive pathogen
subunit
name the vac type from these pros
all benefits of attenuated vaccines
fewer risks because not actual pathogen is used
vectored
name the vac type from these pros
induce humoral and c-mediated response
prolongs expression, enhancing memory
high stability and highly customizable
nucleic acid
name the vac type from these cons
may revert to pathogen form
high side effects and complications
required cold chain
attenuated
name the vac type from these cons
booster required
no replication in host
activates humoral only
more risk involved
innactive
name the vac type from these pros
no reverting
easy transport and storage
innactive
name the vac type from these cons
some attenuated vaccine problems still present
stability issues
patio replication
vectored
name the vac type from these cons
cold chain, unknown
nucleic acid
___: added to vaccine to enhance immune response
adjuvants
___ promote inflammation, slowing Ag release, causing high cell-to-cell interactions and high effectivness
adjuvants
____ stems protective immunity against disease cause pathogens
immunization
___ is the intentional exposure to a modified form of a pathogen
vaccination
___ immunity is exposure to live pathogen –> infection –> recovery
natural
___ immunity: antibody transfers from 1 person to another without activating their B and T cells
passive
__ immunity is beneficial against bacteria and toxins
artifical
___ immunity is about IgG
natural
__ immunity occurs when IgG passes from placenta to fetus or breast milk to infant
natural
what is a use of passive immunity
immune deficiency
immune deficiency can lead to what 2 hyperensativity types
1 and 3