E2: L15 P1 Flashcards
B cells can become ___ presenting cells on their own
antigen
immature B cells have ___ receptors on cell surface
Ig
antigen stimulation –> B cell that matures and ___ to lymphoid organs to ____
migrates, replicate
when immune response is over, memory B cells are capable of mounting an enhanced ___ response
secondary
during embryonic development, B -cells with receptors for self-antigens are ___
deleted
each B-cell receptor is ___
identical
clonal ___ are exactly the same as the parent bcells
descendents
memory cells are post immune response __ cells and are capable of producing an enhansed ___ immune response
B, secondary
the B-celll clonal selection hypothesis was established in the __
60s
clonal receptor hypothesis states that the B cells cloned will be done so to respond to a specific __ and will have a specific ___
antigen, receptor
2 major types of B-cell responses:
1. T-___, pathway for B sub _ cells
2. T-independent
dependent, 2
T-dependent response is generated via a ___ Antigen
protein
T-dependent B cell response is mediated by B-2 B cells binding to __ antigens
TD
important cytokines in a t-dependent response are IL__ and IL__
IL-2 and IL-4
B cells bind to an __ which initiate activation and proliferation events.
antigen
