E3: L23/22 Discussion Flashcards

1
Q

Which of the following conditions is NOT an organ-specific autoimmune disease?

a. Addison’s Disease

b. Myasthenia gravis

c. Multiple Sclerosis

d. all of the above

e. b & c only

A

C

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2
Q

Which of the following mechanisms can induce autoimmunity?

a. molecular mimicry

b. infections causing genetic changes

c. foods that alter gut microbial balance

d. a & b only

e. all of the above

A

E

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3
Q

Which of the following is not a pro-inflammatory environmental factor associated with autoimmune diseases?

a. toxins such as smoking

b. infections

c. physiological or oxidative stress

d. all of the above

e. a & b only

A

D

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4
Q

Which of the following involves a situation where self-tissue is grafted to another self area?

a. isografts

b. autografts

c. allografts

d. xenografts

e. none of the above

A

B

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5
Q

Is multiple sclerosis a systemic autoimmune or organ specific disease?

A

Systemic

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6
Q

Which type of hypersensitivity causes hemolytic disease of the newborn?

A. Type I
B. Type II
C. Type III
D. Type IV
E. None of the above

A

Answer: B. Type II

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7
Q

Delayed-type hypersensitivites are generally caused by_______

a. antibody-antigen reactions

b. T-cell reactions

c. macrophages

d. mast cells

A

B

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8
Q

Food allergy is what type of hypersensitivity?

A

1

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9
Q

Which hypersensitivity type uses complement, antibody dependent cell mediated cytotoxicity, and opsonization?

A

2

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10
Q

. What does the FcεRII (CD23) regulate?

A

the Increasing/Decreasing production of IgE by B cells

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11
Q

If a Mast cell is expressing both FcεRII (activating) and FcγRIIB (inhibiting) Ig receptors and it binds to a IgE and IgG, the activating signal is induced. (True/False)

A

False
When the both are binded the inhibiting signal is induced

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12
Q

T/F: hemolytic anemia can be drug induced.

A

True

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