Discussion Post Qs Flashcards
the variable regions of receptors and antibodies are capable of high diversity because of ___ ___
gene recombination
the ___ ___ of receptors and antibodies are capable of high diversity because of gene recombination
variable regions
Can MHC cells interact with both MHC 1 and 2?
yes
if the 2 process signal is disturbed, it becomes ___
anergic
anergy is dependent on __-___
co-stimulation
Which Ig has the longest half life
IgG
Which Ig is the first to arrive on scene
IgM
T/F: Can T helper cells shift subsets
False
The type 2 pathogen response is initiated by?
A. Viruses
B. Bacteria
C. CD8+ cell binds to MHC 1 receptor to induce apoptosis
D. Worms
Worms
T/F - Early in differentiation, Th cells may be able to shift between subsets.
True
Which of the following cytotoxic cells are involved in organ transplant rejection
a. NK cells b. NKT lymphocytes c. CD8+ cytotoxic T lymphocytes d. A and C e. All of the above
D
Which of the following cytotoxic cells is an innate lymphoid cell that lacks specific antigen receptors?
a. NKT lymphocytes b. NK cells c. CD8+ cytotoxic T lymphocytes d. A and B e. All of the above
B
Which of the folling Th subsets is involved in sepressing immune response?
a. Th1 cells b. Peripheral Treg cells c. Th2 cells d. Tfh cells
B
Which of the following Th subsets regulates affinity maturation of germinal center B cells
a. Tfh cells b. Th1 cells c, Th2 cells d. Peripheral Treg cells
A
Where does FcRs bind to
Fc regions of antibodies
The 3 high-affinity FcERI cells are?
Mast cells, esoinophils, and basophils
The 2 low-affinity FcER cells are?
B cells and eosinophils
PolygR stands for
Polymeric Immunoglobulin
FcRn stands for
neonatal Fc receptor
Which antibody mediated effector responses from the immunoglobulins depend on FcR? OAD
Opposition, ADCC, degranulation
Which FcR is the main mediator of antibody functions?
FcR-gamma
Which FcR initiates transcytosis of IgA and IgM from blood to lumen of GI, respiratory, or reproductive tract?
Fc PolyIgR
What immunoglobulin does FcR-gamma bind?
IgG
- __ First antibody produced upon infection
IgM
- __ Protects mucous membranes
IgA
- __ Protects against all types of infections and is most abundant.
IgG
- __ Defends against allergens and is found on the surface of basophils and mast cells.
IgE
- __ Found on the surface of B cells.
IgD
Which type of outcome (6 types) from antibody binding to antigen causes the antibody to bind to multiple antigens, and cross-links them for phagocytosis in large groups?
Aggulation
