Drugs Affecting Blood Coagulation

Question 1

Heparin

Answer 1

Prevention and treatment of venous thrombosis and pulmonary emboli

treatment of atrial fibrillation with embolization

diagnosis and treatment of disseminated intravascular coagulation

prevention of clotting in blood samples and heparin lock sets.

Question 2

Heparin actions

Answer 2

Inhibits thrombus and clot production by blocking the conversion of prothrombin to thrombin and fibrinogen to fibrin

Question 3

Heparin adverse effects

Answer 3

Loss of hair , osteoporosis, bruising

suppression of renal funcion (with long term use)

Question 4

Warfarin

Answer 4

Treatment of patients with AF, artificial heart valves, or valvular damage that makes PT susceptible to thrombus and embolus formation;
prevention and treatment of VTE, pulmonary embolus, and systemic emboli after MI