Chapter 52- Drugs & UT & Bladder Flashcards
How are the two types of urinary tract anti-infective’s different?
Those drugs with an antibiotic effect interfere with reproduction of the gram-negative bacteria and those that cause acidification of the urine produce an environment that is not conducive to bacterial survival.
What are the indications of Norfloxacin?
Treatment of adults with UTIs caused by susceptible strains of bacteria; uncomplicated urethral and cervical gonorrhea; prostitis caused by E. coli.
What are the actions of Norfloxacin?
Interferes with DNA replication insusceptible gram-negative bacteria leading to cell death
What are some adverse effects of norfloxacin?
Headache dizziness nausea vomiting fever rash photosensitivity
What kind of drug is oxybutynin and what are its indications?
Urinary tract anti-spasmodic.
Relief of symptoms of bladder instability associated with uninhibited neurogenic and reflex neurogenic bladder or; treatment of signs and symptoms of overactive bladder.
What are the actions of oxybutynin?
Acts directly to relax smooth muscle in the bladder; inhibits that effects of acetylcholine at muscarinic receptors.
What are some adverse effects of oxybutynin?
Drowsiness, dizziness, blurred vision, decreased sweating, urinary hesitancy
What kind of drug is phenazopryidine and what are its indications?
Urinary tract analgesic.
Symptomatic relief of pain, urgency, burning, frequency, and discomfort related to lower urinary tract irritation caused by infection, Trauma, surgery, or various procedures
What are the actions of phenazopryidine?
Has a direct, topical analgesic effects on the urinary tract mucosa; mechanism of action is not known
What are some adverse effects of phenazopryidine ?
Headache; rash; yellowish tinge to skin, sclera, urine; and gastrointestinal disturbances.
What are the signs and symptoms of a UTI?
Urinary frequency, urgency, burning on urination, chills, fever, flank pain, tenderness
What kind of drug is doxazosin and what are its indications,?
Drugs for treating benign prosthetic hyperplasia.
Treatment of BPH
What are the actions of doxazosin?
Blocks postsynaptic alpha-1 adrenergic receptors, which results in a dilation of arterials and veins and relaxation of sympathetic effects on the bladder and urinary tract.
What are the adverse affects of doxazosin?
Headache fatigue dizziness postural dizziness diarrhea sexual dysfunction palpitations
