drug formulations and patient counseling Flashcards
olanzapine (zyprexa) formulations available
IR tablet
ODT tablet
short acting injection
long acting injection
ondansetron (zofran) MOA
5 HT3 receptor antagonist
zofran formulations
IR tablet ODT tablet oral solution oral film short acting injection
sanusco (granistron)
patch!
patch applied before chemotherapy and can prevent nausea for up to 7 days
sorbitol is used as a sweetener in many meds but can cause problems in patients with
IBS
____ is used in many ODT, chewable and granule formulations it is a dangerous sweetener in patients wit hphenylketonuria (PKU)
phenylananine
onzetra xsail
nasal powder for migraine
cotempla xr- odt
long acting odt for adhd
ODTs how used
placed on the tongue
disingrates rapidly with saliva
ODT examples
lamictal ODT- lamotrigine for children
Remeron solutab- mirtazipine, for nausea, dysphagia
Zyrexa Zydis- olanzapine, for non adherence
Ondansetron ODT- nausea, dysphagia
dysphagia
difficulty swallowing
if vomiting present use
non oral route
zuplenz
ondansetron oral film
sublingual or buccal delivery can be with
a tablet, film, powder, or spray
examples of sublingual
edluar and intermezzo- zolpidem SL tabs (fast onset)
nitrostat- SL (fast onset)
subsys, actiq, fentora -fentanyl (fast onset)
lozenges are used to treat
conditions in the oral mucosa
drug is held in the mouth while is slowly dissolves
lozenge example
mycelex- clotrimazole troche for oral thrush
chewable tablets examples
suprax- cefixime, for children
singulair- montelukast, for kids
lamictal CD- lamotrigine, for kids
granules (can be opened or sprinkled into soft food or water)
on applesauce: adderall XR coreg CR dexilant focalin XR namenda XR nexium ritalin LA
counseling points for granules
- do not chew long acting pellets or beads that are emptied out from capsule
- do not let the mixture sit too long
- do not add to anything warm or hot
long acting oral tablets/capsules examples
concerta- methylphenidate
detrol la- tolterodine
do not crush or chew long acting formulations
XL XR ER LA SR CR CRT SA TR TD 24 time caps sprinkles "cont"
OROS ghost tablet few examples
concerta cardura xl procardia xl asacol hd delzicol
extended release that can be cut at the score line but not crushed or chewed
toprol xl
sinemet CR
bactroban
mupirocin oint. for skin infec.
androgel
testosterone for systemic effect
used as an alternative to injections
SC injections examples
forteo- teriparatide imitrex- sumatriptan insulins, glp 1 agonists lovenox- enoxaparin tymlos- abaloparatide`
long acting IM injections
abilify maintena haldol invega sustenna, invega trinza- paliperidone lupron depot- leuprolide risperdol consta- risperidone vivitrol- naltrexone zyprexa relprevv- olanzapine
golimumab (simponi)
monthly
etanercept (enbrel)
weekly
adalimumab (humira)
every other week (biweekly)
enoxaparin and fondaparinux give
once or twice daily
in the abdomen greater than 1 inch from navel
most patches can be placed
upper chest
lower and upper back
upper arm (part facing out)
flanks (sides of the body abdomen level)
exelon cannot be applied to the
flanks
the only patch you can cut
lidoderm
most patches cannot be covered with
tape
a few can be taped around the edges
fentanyl (duragesic) and buprenorphine (butrans)
can be covered only with the permiited adhesive film dressings (bioclusive and tegaderm)
____ comes with its own adhesive cover which goes over the patch to hold it in place
catapres tts
daytrana is applied on the
HIP alternating right and left daily
transderm scop is applied behind the
ear and needs to be applied at least 4 hours before needed alternating ears every 72 hours
vivelle dot apply
lower abdomen
xulane apply
back abdomen buttock
oxybutynin apply
hip abdomen buttock
daytrana (methylphenidate patch) frequency
every morning
2 hours prior to school
nicoderm patch
daily
exelon patch (rivastigmine)
daily
rotigotine
daily
selgiline patch
daily
testosterone patch
nightly not on scrotum
lidocaine patch instructions
1-3 patches
on for 12 hours then off for 12 hours as needed
nitroglycerin patch
on for 12-14 hours then off for 10-12 hours
DIclofenac patch
twice daily
vivelle dot frequency
twice weekly
oxybutynin patch frequency
twice weekly
butrans patch
weekly
clonidine patch (catapres tts)
weekly
estradiol (climara) patch
weekly
estradiol/levonorgestrol patch
weekly
xulane patch
weekly for 3 weeks of for 4th week
fentanyl(duragesic) and scopalamine patch
every 72 hours change patch
do not rub skin near ____ injections rubbing can cause severe brusing
anticoagulant injections
enoxaparin, fondaparinux
injection steps
wash hands prepare injection clean injection site inject discard into sharps
-mabs (monoclonal) specifics
do not shake (will denature proteins)
avoid exposing to extreme hots or colds
store in fridge
bring to room temp prior to injecting
nasal spray counseling
1) SHAKE gently and remove cap
2) PRIME before first use, or if its been 7-14 days
3) BLOW YOUR NOSE
4) CLOSE ONE NOSTRIL
5) BREATHE IN through your NOSE, press down
6) BREATHE OUT trough MOUTH
7) wipe with a tissue, replace cap
8) use for labeled number of sprays then discard even if not empty
9) do NOT BLOW your NOSE right after using
wait at least _____ minutes to put a second medication in your eye
5-10
gels are 10 minutes
if the eye drop contains the preservative benzalkonium chloride (BAK) and you wear soft contact lenses remove them prior to insertion and wait __ minutes until you put them back in
15 minutes
do not drop cold __ into ear
ear drops
ear drops that are too cold can cause dizziness
shake or roll bottle in the in your hands for 1-2 minutes
for ear drops how is it different adults to children
adults pull ear up and back
children less then 3 down and back
after administering ear drops keep the ear facing up for about __ minutes to coat the ear canal
5 minutes
