drug formulations and patient counseling Flashcards

1
Q

olanzapine (zyprexa) formulations available

A

IR tablet
ODT tablet
short acting injection
long acting injection

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2
Q

ondansetron (zofran) MOA

A

5 HT3 receptor antagonist

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3
Q

zofran formulations

A
IR tablet
ODT tablet
oral solution
oral film
short acting injection
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4
Q

sanusco (granistron)

A

patch!

patch applied before chemotherapy and can prevent nausea for up to 7 days

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5
Q

sorbitol is used as a sweetener in many meds but can cause problems in patients with

A

IBS

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6
Q

____ is used in many ODT, chewable and granule formulations it is a dangerous sweetener in patients wit hphenylketonuria (PKU)

A

phenylananine

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7
Q

onzetra xsail

A

nasal powder for migraine

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8
Q

cotempla xr- odt

A

long acting odt for adhd

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9
Q

ODTs how used

A

placed on the tongue

disingrates rapidly with saliva

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10
Q

ODT examples

A

lamictal ODT- lamotrigine for children
Remeron solutab- mirtazipine, for nausea, dysphagia
Zyrexa Zydis- olanzapine, for non adherence
Ondansetron ODT- nausea, dysphagia

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11
Q

dysphagia

A

difficulty swallowing

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12
Q

if vomiting present use

A

non oral route

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13
Q

zuplenz

A

ondansetron oral film

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14
Q

sublingual or buccal delivery can be with

A

a tablet, film, powder, or spray

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15
Q

examples of sublingual

A

edluar and intermezzo- zolpidem SL tabs (fast onset)
nitrostat- SL (fast onset)
subsys, actiq, fentora -fentanyl (fast onset)

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16
Q

lozenges are used to treat

A

conditions in the oral mucosa

drug is held in the mouth while is slowly dissolves

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17
Q

lozenge example

A

mycelex- clotrimazole troche for oral thrush

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18
Q

chewable tablets examples

A

suprax- cefixime, for children
singulair- montelukast, for kids
lamictal CD- lamotrigine, for kids

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19
Q

granules (can be opened or sprinkled into soft food or water)

A
on applesauce:
adderall XR
coreg CR
dexilant
focalin XR
namenda XR
nexium
ritalin LA
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20
Q

counseling points for granules

A
  • do not chew long acting pellets or beads that are emptied out from capsule
  • do not let the mixture sit too long
  • do not add to anything warm or hot
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21
Q

long acting oral tablets/capsules examples

A

concerta- methylphenidate

detrol la- tolterodine

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22
Q

do not crush or chew long acting formulations

A
XL
XR
ER
LA
SR
CR
CRT
SA
TR
TD
24
time caps 
sprinkles
"cont"
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23
Q

OROS ghost tablet few examples

A
concerta 
cardura xl
procardia xl
asacol hd
delzicol
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24
Q

extended release that can be cut at the score line but not crushed or chewed

A

toprol xl

sinemet CR

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25
bactroban
mupirocin oint. for skin infec.
26
androgel
testosterone for systemic effect | used as an alternative to injections
27
SC injections examples
``` forteo- teriparatide imitrex- sumatriptan insulins, glp 1 agonists lovenox- enoxaparin tymlos- abaloparatide` ```
28
long acting IM injections
``` abilify maintena haldol invega sustenna, invega trinza- paliperidone lupron depot- leuprolide risperdol consta- risperidone vivitrol- naltrexone zyprexa relprevv- olanzapine ```
29
golimumab (simponi)
monthly
30
etanercept (enbrel)
weekly
31
adalimumab (humira)
every other week (biweekly)
32
enoxaparin and fondaparinux give
once or twice daily | in the abdomen greater than 1 inch from navel
33
most patches can be placed
upper chest lower and upper back upper arm (part facing out) flanks (sides of the body abdomen level)
34
exelon cannot be applied to the
flanks
35
the only patch you can cut
lidoderm
36
most patches cannot be covered with
tape
37
a few can be taped around the edges
fentanyl (duragesic) and buprenorphine (butrans) | can be covered only with the permiited adhesive film dressings (bioclusive and tegaderm)
38
____ comes with its own adhesive cover which goes over the patch to hold it in place
catapres tts
39
daytrana is applied on the
HIP alternating right and left daily
40
transderm scop is applied behind the
ear and needs to be applied at least 4 hours before needed alternating ears every 72 hours
41
vivelle dot apply
lower abdomen
42
xulane apply
back abdomen buttock
43
oxybutynin apply
hip abdomen buttock
44
daytrana (methylphenidate patch) frequency
every morning | 2 hours prior to school
45
nicoderm patch
daily
46
exelon patch (rivastigmine)
daily
47
rotigotine
daily
48
selgiline patch
daily
49
testosterone patch
nightly not on scrotum
50
lidocaine patch instructions
1-3 patches | on for 12 hours then off for 12 hours as needed
51
nitroglycerin patch
on for 12-14 hours then off for 10-12 hours
52
DIclofenac patch
twice daily
53
vivelle dot frequency
twice weekly
54
oxybutynin patch frequency
twice weekly
55
butrans patch
weekly
56
clonidine patch (catapres tts)
weekly
57
estradiol (climara) patch
weekly
58
estradiol/levonorgestrol patch
weekly
59
xulane patch
weekly for 3 weeks of for 4th week
60
fentanyl(duragesic) and scopalamine patch
every 72 hours change patch
61
do not rub skin near ____ injections rubbing can cause severe brusing
anticoagulant injections | enoxaparin, fondaparinux
62
injection steps
``` wash hands prepare injection clean injection site inject discard into sharps ```
63
-mabs (monoclonal) specifics
do not shake (will denature proteins) avoid exposing to extreme hots or colds store in fridge bring to room temp prior to injecting
64
nasal spray counseling
1) SHAKE gently and remove cap 2) PRIME before first use, or if its been 7-14 days 3) BLOW YOUR NOSE 4) CLOSE ONE NOSTRIL 5) BREATHE IN through your NOSE, press down 6) BREATHE OUT trough MOUTH 7) wipe with a tissue, replace cap 8) use for labeled number of sprays then discard even if not empty 9) do NOT BLOW your NOSE right after using
65
wait at least _____ minutes to put a second medication in your eye
5-10 | gels are 10 minutes
66
if the eye drop contains the preservative benzalkonium chloride (BAK) and you wear soft contact lenses remove them prior to insertion and wait __ minutes until you put them back in
15 minutes
67
do not drop cold __ into ear
ear drops ear drops that are too cold can cause dizziness shake or roll bottle in the in your hands for 1-2 minutes
68
for ear drops how is it different adults to children
adults pull ear up and back | children less then 3 down and back
69
after administering ear drops keep the ear facing up for about __ minutes to coat the ear canal
5 minutes